Minocycline
{{DrugProjectFormSinglePage |authorTag=Ammu Susheela, M.D. [1] |genericName=Minocycline |aOrAn=a |drugClass=tetracycline antiobiotic |indicationType=treatment |indication=is indicated as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis. Minocycline may be used as part of a periodontal maintenance program which includes good oral hygiene, and scaling and root planing |adverseReactions=the most frequently reported nondental treatment-emergent adverse events in the 3 multicenter US trials were headache, infection, flu syndrome, and pain. Dental conditions include peritonitis, gingivitis, stomatitis, pharyngitis |blackBoxWarningTitle=TITLE |blackBoxWarningBody=Condition Name: (Content) |fdaLIADAdult=Minocycline is indicated as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis. Minocycline may be used as part of a periodontal maintenance program which includes good oral hygiene, and scaling and root planing. |offLabelAdultGuideSupport=There is limited information regarding Off-Label Guideline-Supported Use of Minocycline in adult patients. |offLabelAdultNoGuideSupport=There is limited information regarding Off-Label Non–Guideline-Supported Use of Minocycline in adult patients. |offLabelPedGuideSupport=There is limited information regarding Off-Label Guideline-Supported Use of Minocycline in pediatric patients. |offLabelPedNoGuideSupport=There is limited information regarding Off-Label Non–Guideline-Supported Use of Minocycline in pediatric patients. |contraindications=It should not be used in any patient who has a known sensitivity to tetracyclines. |clinicalTrials=* This medication may cause upset stomach, diarrhea, dizziness, unsteadiness, drowsiness, headache or vomiting. If these symptoms persist or worsen, one should notify their doctor. Minocycline increases sensitivity to sunlight. Prolonged sun exposure should be avoided. Wear protective clothing and use a sunscreen if needed. Very unlikely but should be reported: fever, yellowing of the eyes or skin, stomach pain, sore throat, vision changes and mental changes.
- In those cases where this drug must be used for extended periods, blue-gray skin discoloration may occur. In the unlikely event one has an allergic reaction to this drug, immediate medical attention should be sought. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, trouble breathing. Other effects not listed above should be reported to the doctor or pharmacist.
|administration=* Oral |drugBox=
|howSupplied=* Minocycline equivalent to 50 mg minocycline are opaque white capsules imprinted "0487" and "DYNACIN® 50 mg" and are supplied as follows: NDC 99207-487-10 Bottles of 100 NDC 99207-487-11 Bottle of 1000.
- Minocycline equivalent to 75 mg minocycline are light gray opaque capsules imprinted "0489" and "DYNACIN® 75 mg" and are supplied as follows:
NDC 99207-489-10 Bottles of 100 NDC 99207-489-11 Bottle of 1000.
- Minocycline equivalent to 100 mg minocycline are opaque dark gray and opaque white capsules imprinted "0488" and "DYNACIN® 100 mg" and are supplied as follows:
NDC 99207-488-05 Bottles of 50 NDC 99207-488-11 Bottle of 1000.
- Dispense in tight, light-resistant container with child-resistant closure.
- Store at 20º–25ºC (68º–77ºF).
- Protect from light, moisture and excessive heat.
|packLabel=
|alcohol=Alcohol-Minocycline interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication. |brandNames=*MINOCYCLINE HYDROCHLORIDE ®[2]