Middle East respiratory syndrome coronavirus infection historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
Human infection with a novel coronavirus named Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia and the Middle East in September, 2012, with 44 laboratory-confirmed cases as of May 23, 2013. Egyptian virologist Dr. Ali Mohamed Zaki identified the virus on a patient on june 13 2012 in a hospital in Jeddah, Soudi Arabia. Another case of a 44 year old man with similar symptoms was reported in Qatar in September 2012. In November 2012 similar cases appeared in Qatar and Soudi Arabia. It has been determined through molecular clock analysis, that viruses from the EMC/2012 and England/Qatar/2012 date to early 2011 suggesting that these cases are descended from a single zoonotic event. It would appear the MERS-CoV has been circulating in the human population for greater than one year without detection and suggests independent transmission from an unknown source.<ref name=" | Human infection with a novel coronavirus named Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia and the Middle East in September, 2012, with 44 laboratory-confirmed cases as of May 23, 2013. Egyptian virologist Dr. Ali Mohamed Zaki identified the virus on a patient on june 13 2012 in a hospital in Jeddah, Soudi Arabia. Another case of a 44 year old man with similar symptoms was reported in Qatar in September 2012. In November 2012 similar cases appeared in Qatar and Soudi Arabia. It has been determined through molecular clock analysis, that viruses from the EMC/2012 and England/Qatar/2012 date to early 2011 suggesting that these cases are descended from a single zoonotic event. It would appear the MERS-CoV has been circulating in the human population for greater than one year without detection and suggests independent transmission from an unknown source.<ref name="pmid23693015">{{cite journal| author=Cotten M, Lam TT, Watson SJ, Palser AL, Petrova V, Grant P et al.| title=Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus. | journal=Emerg Infect Dis | year= 2013 | volume= 19 | issue= 5 | pages= 736-42B | pmid=23693015 | doi=10.3201/eid1905.130057 | pmc=PMC3647518 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23693015 }} </ref> | ||
==References== | ==References== | ||
Revision as of 18:53, 17 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first reported to cause human infection in September 2012. In July 2013, the World Health Organization (WHO) International Health Regulations Emergency Committee determined that MERS-CoV did not meet criteria for a "public health emergency of international concern," but was nevertheless of "serious and great concern".
Historical Perspective
Human infection with a novel coronavirus named Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia and the Middle East in September, 2012, with 44 laboratory-confirmed cases as of May 23, 2013. Egyptian virologist Dr. Ali Mohamed Zaki identified the virus on a patient on june 13 2012 in a hospital in Jeddah, Soudi Arabia. Another case of a 44 year old man with similar symptoms was reported in Qatar in September 2012. In November 2012 similar cases appeared in Qatar and Soudi Arabia. It has been determined through molecular clock analysis, that viruses from the EMC/2012 and England/Qatar/2012 date to early 2011 suggesting that these cases are descended from a single zoonotic event. It would appear the MERS-CoV has been circulating in the human population for greater than one year without detection and suggests independent transmission from an unknown source.[1]
References
- ↑ Cotten M, Lam TT, Watson SJ, Palser AL, Petrova V, Grant P; et al. (2013). "Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus". Emerg Infect Dis. 19 (5): 736–42B. doi:10.3201/eid1905.130057. PMC 3647518. PMID 23693015.