Mebendazole: Difference between revisions
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Revision as of 21:20, 8 January 2014
For patient information, click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Mebendazole is a benzimidazole drug that is used to treat infestations by worms including pinworms,roundworms, tapeworms, hookworms, and whipworms. The active ingredient in Pripsen powder is piperazine.
Category
Anthelmintic
US Brand Names
MEBENDAZOLE®
FDA Package Insert
Description | Clinical Pharmacology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Mebendazole (C16H13N3O3) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. It is a spindle poison that induces chromosome nondisjunction.