Mebendazole: Difference between revisions
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'''| [[Mebendazole drug interactions|Drug Interactions]]''' | '''| [[Mebendazole drug interactions|Drug Interactions]]''' | ||
'''| [[Mebendazole overdosage|Overdosage]]''' | '''| [[Mebendazole overdosage|Overdosage]]''' | ||
'''| [[Mebendazole dosage and administration|Dosage and Administration]]''' | '''| [[Mebendazole dosage and administration|Dosage and Administration]]''' | ||
'''| [[Mebendazole how supplied|How Supplied]]''' | '''| [[Mebendazole how supplied|How Supplied]]''' | ||
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==Mechanism of Action== | ==Mechanism of Action== | ||
Mebendazole ([[Carbon|C]]<sub>16</sub>[[Hydrogen|H]]<sub>13</sub>[[Nitrogen|N]]<sub>3</sub>[[Oxygen|O]]<sub>3</sub>) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where [[helminths]] dwell. It is a [[spindle poison]] that induces [[chromosome]] [[nondisjunction]]. | Mebendazole ([[Carbon|C]]<sub>16</sub>[[Hydrogen|H]]<sub>13</sub>[[Nitrogen|N]]<sub>3</sub>[[Oxygen|O]]<sub>3</sub>) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where [[helminths]] dwell. It is a [[spindle poison]] that induces [[chromosome]] [[nondisjunction]]. | ||
Revision as of 20:47, 6 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Mebendazole is a benzimidazole drug that is used to treat infestations by worms including pinworms,roundworms, tapeworms, hookworms, and whipworms. The active ingredient in Pripsen powder is piperazine.
Category
Anthelmintic
US Brand Names
MEBENDAZOLE®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Mebendazole (C16H13N3O3) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. It is a spindle poison that induces chromosome nondisjunction.