Mebendazole: Difference between revisions

Revision as of 20:31, 6 January 2014

Mebendazole
MEBENDAZOLE^® FDA Package Insert
Description
Clinical Pharmacology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mebendazole is a benzimidazole drug that is used to treat infestations by worms including pinworms,roundworms, tapeworms, hookworms, and whipworms. The active ingredient in Pripsen powder is piperazine.

US Brand Names

MEBENDAZOLE

FDA Package Insert

Mechanism of Action

References

Mechanism

Mebendazole (C₁₆H₁₃N₃O₃) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. It is a spindle poison that induces chromosome nondisjunction.

Dosage

Oral dosage is 100 mg 12 hourly for 3 days, although sometimes the dosage is just one 500 mg dose, followed by another dose two weeks later if the infection has not cleared up. The dosage may differ depending on which type of worm someone is infected with.

External links

Vermox (UK manufacturer's website)

Template:Pharma-stub Template:Anthelmintics hu:Mebendazol nl:Mebendazol Template:WikiDoc Sources

@@ Line 1: / Line 1: @@
-''This article is about a pharmaceutical drug, for the automobile brand abbreviated as [[MBZ]], see [[Mercedes-Benz]]''
+__NOTOC__
-{{Drugbox|
+{{Mebendazole}}
-|IUPAC_name = methyl [(5-benzoyl-3H-benzoimidazol-2-yl)amino]formate
+{{CMG}}
-| image = Mebendazole.png
-| width=320
+==Overview==
-| CAS_number=31431-39-7
-| ATC_prefix=P02
+'''Mebendazole''' is a [[benzimidazole]] drug that is used to treat infestations by [[worm]]s including [[pinworm]]s,[[roundworm]]s, [[tapeworm]]s, [[hookworm]]s, and [[whipworm]]s. The active ingredient in Pripsen powder is piperazine.
-| ATC_suffix=CA01
-| ATC_supplemental=
+==Category==
-| PubChem=7847434
-| DrugBank=APRD01086
+Anthelmintics
-| C=16 | H=13 | N=3 | O=3
-| molecular_weight = 295.293 g/mol
+==US Brand Names==
-| bioavailability= ?
-| metabolism = Hepatic
+MEBENDAZOLE
-| elimination_half-life= 2.5 to 5.5 hours
-| excretion = ?
+==FDA Package Insert==
-| pregnancy_category = ?
-| legal_status = ?
+'''  [[Mebendazole description|Description]]'''
-| routes_of_administration= Oral
+'''| [[Mebendazole clinical pharmacology|Clinical Pharmacology]]'''
-}}
+'''| [[Mebendazole microbiology|Microbiology]]'''
-'''Mebendazole''' or '''MBZ''', marketed as Ovex, Vermox, Antiox or Pripsen, is a [[benzimidazole]] drug that is used to treat infestations by [[worm]]s including [[pinworm]]s, [[roundworm]]s, [[tapeworm]]s, [[hookworm]]s, and [[whipworm]]s. The active ingredient in Pripsen powder is piperazine.
+'''| [[Mebendazole indications and usage|Indications and Usage]]'''
+'''| [[Mebendazole contraindications|Contraindications]]'''
+'''| [[Mebendazole warnings and precautions|Warnings and Precautions]]'''
+'''| [[Mebendazole adverse reactions|Adverse Reactions]]'''
+'''| [[Mebendazole drug interactions|Drug Interactions]]'''
+'''| [[Mebendazole overdosage|Overdosage]]'''
+'''| [[Mebendazole clinical studies|Clinical Studies]]'''
+'''| [[Mebendazole dosage and administration|Dosage and Administration]]'''
+'''| [[Mebendazole how supplied|How Supplied]]'''
+'''| [[Mebendazole labels and packages|Labels and Packages]]'''
+==Mechanism of Action==
+==References==
+{{Reflist|2}}
+[[Category:Antibiotics]]
+[[Category:Wikinfect]]
 ==Mechanism==