Mast cell tumor: Difference between revisions

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{{Infobox_Disease |
  Name          = {{PAGENAME}} |
  Image          = |
  Caption        = |
  DiseasesDB    = 34450 |
  ICD10          = {{ICD10|C|96|2|c|81}}, {{ICD10|D|47|0|d|37}} |
  ICD9          = {{ICD9|238.5}} |
  ICDO          = |
  OMIM          = |
  MedlinePlus    = |
  MeshID        = D034801 |
}}
{{Mast cell tumor}}
{{Mast cell tumor}}
{{CMG}};{{AE}}{{PSK}}


==Overview==
{{SK}} Mastocytosis; Systemic mastocytosis; Cutaneous mastocytosis; Systemic mast cell tumor; Cutaneous mast cell tumor; Mastocytoma; Mast cell neoplasm; Localized mastocytosis; Maculopapular cutaneous mastocytosis; Diffuse cutaneous mastocytosis; Mastocytoma of skin; Indolent systemic mastocytosis; Smoldering systemic mastocytosis; Isolated bone marrow mastocytosis; Aggressive systemic mastocytosis; Mast cell sarcoma; Extracutaneous mastocytoma; Mastocyte tumor


A mast cell originates from the [[bone marrow]] and is normally found throughout the [[connective tissue]] of the body.  It is a normal component of the [[immune system]] and as it releases [[histamine]] it is associated with [[allergy|allergic reaction]]s.  Mast cells also respond to tissue [[physical trauma|trauma]].  Mast cell [[granule]]s contain histamine, [[heparin]], [[platelet-activating factor]], and other substances.  Disseminated [[mastocytosis]] is rarely seen in young dogs and cats, while mast cell tumors are a common [[malignant]] tumor of the skin in older dogs and cats.  Up to 20 to 25 percent of skin tumors in dogs are mast cell tumors,<ref name=saph>{{cite journal |author=Brière C |title=Use of a reverse saphenous skin flap for the excision of a grade II mast cell tumor on the hind limb of a dog |journal=Can Vet J |volume=43 |issue=8 |pages=620-2 |year=2002 |id=PMID 12170840}}</ref> with a similar number in cats.<ref name=pathol>{{cite journal |author=Johnson T, Schulman F, Lipscomb T, Yantis L |title=Histopathology and biologic behavior of pleomorphic cutaneous mast cell tumors in fifteen cats |journal=Vet Pathol |volume=39 |issue=4 |pages=452-7 |year=2002 |id=PMID 12126148}}</ref>
==[[Mast cell tumor overview|Overview]]==


==References==
==[[Mast cell tumor historical perspective|Historical Perspective]]==
{{Reflist|2}}
 
==[[Mast cell tumor classification|Classification]]==
 
==[[Mast cell tumor pathophysiology|Pathophysiology]]==
 
==[[Mast cell tumor causes|Causes]]==
 
==[[Mast cell tumor differential diagnosis|Differentiating Mast Cell Tumor from other Diseases]]==
 
==[[Mast cell tumor epidemiology and demographics|Epidemiology and  Demographics]]==
 
==[[Mast cell tumor risk factors|Risk Factors]]==
 
==[[Mast cell tumor screening|Screening]]==
 
==[[Mast cell tumor natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
[[Mast cell tumor diagnostic criteria|Diagnostic Criteria]] | [[Mast cell tumor staging|Staging]] | [[Mast cell tumor history and symptoms|History and Symptoms]] | [[Mast cell tumor physical examination|Physical Examination]] | [[Mast cell tumor laboratory findings|Laboratory Findings]] | [[Mast cell tumor Electrocardiogram|Electrocardiogram]] | [[Mast cell tumor x ray|X-Ray Findings]] | [[Mast cell tumor echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Mast cell tumor CT scan|CT-Scan Findings]] | [[Mast cell tumor MRI|MRI Findings]] | [[Mast cell tumor biopsy|Biopsy]] | [[Mast cell tumor other imaging findings|Other Imaging Findings]] | [[Mast cell tumor other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Mast cell tumor medical therapy|Medical Therapy]] | [[Mast cell tumor surgery|Surgery]] | [[Mast cell tumor cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Mast cell tumor future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Mast cell tumor case study one|Case #1]]
 
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Oncology]]


[[Category:Pathology]]
[[Category:Pathology]]
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Latest revision as of 20:55, 6 December 2018

Mast cell tumor Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Synonyms and keywords: Mastocytosis; Systemic mastocytosis; Cutaneous mastocytosis; Systemic mast cell tumor; Cutaneous mast cell tumor; Mastocytoma; Mast cell neoplasm; Localized mastocytosis; Maculopapular cutaneous mastocytosis; Diffuse cutaneous mastocytosis; Mastocytoma of skin; Indolent systemic mastocytosis; Smoldering systemic mastocytosis; Isolated bone marrow mastocytosis; Aggressive systemic mastocytosis; Mast cell sarcoma; Extracutaneous mastocytoma; Mastocyte tumor

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Mast Cell Tumor from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria | Staging | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Biopsy | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1



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