Magnesium oxide: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
No edit summary
Line 40: Line 40:


<!--Contraindications-->
<!--Contraindications-->
|contraindications=
|contraindications=<!--Warnings-->
 
<!--Warnings-->
|warnings=Do Not Use
|warnings=Do Not Use
Do not take more than 2 tablets in a 24 hour period or use the maximum dosage of this product for more than two weeks, except under the advice and supervision of a physician. May have a laxative effect.
Do not take more than 2 tablets in a 24 hour period or use the maximum dosage of this product for more than two weeks, except under the advice and supervision of a physician. May have a laxative effect.
Line 128: Line 126:
<!--Postmarketing Experience-->
<!--Postmarketing Experience-->
|postmarketing=Laxative adverse reaction
|postmarketing=Laxative adverse reaction
|drugInteractions=
|drugInteractions=<!--Use in Specific Populations-->
 
<!--Use in Specific Populations-->
|useInPregnancyFDA=* If pregnant or breast feeding, ask a health professional before use.
|useInPregnancyFDA=* If pregnant or breast feeding, ask a health professional before use.
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
|useInPregnancyAUS=* '''Australian Drug Evaluation Committee (ADEC) Pregnancy Category'''
Line 148: Line 144:
<!--Administration and Monitoring-->
<!--Administration and Monitoring-->
|administration=* Oral
|administration=* Oral
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.


Line 163: Line 157:


<!--Drug box 2-->
<!--Drug box 2-->
|drugBox=<!--Mechanism of Action-->
|drugBox={{Chembox2
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 414322178
| ImageFile = Magnesium chemb.png
| IUPACName = Magnesium oxide
| OtherNames = Magnesia<br/>[[Periclase]]
|Section1={{Chembox Identifiers
| CASNo = 1309-48-4
| CASNo_Ref = {{cascite|correct|CAS}}
| EINECS = 215-171-9
| PubChem = 14792
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1200572
| InChI =
| RTECS = OM3850000
| ATCCode_prefix = A02
| ATCCode_suffix = AA02
| ATC_Supplemental = {{ATC|A06|AD02}}, {{ATC|A12|CC10}}
}}
|Section2={{Chembox Properties
| Formula = MgO
| MolarMass = 40.3044 g/mol
| Appearance = White powder
| Odor = Odorless
| Density = 3.58 g/cm<sup>3</sup>
| MeltingPtC = 2852
| BoilingPtC = 3600
| Solubility = 0.00062 g/100 mL (0 °C) <br> 0.0086 g/100 mL (30 °C)
| SolubleOther = Soluble in [[acid]], [[ammonia]] <br> insoluble in [[alcohol]]
| ThermalConductivity = 45–60&nbsp;W·m<sup>−1</sup>·K<sup>−1</sup><ref>[http://www.konoshima.co.jp/en/resdev/004.html Application of magnesium compounds to insulating heat-conductive fillers]. konoshima.co.jp</ref>
| RefractIndex = 1.7355
| BandGap = 7.8 eV<ref>{{cite journal |journal=Solid State Communications |volume=55 |year=1985 |pages=351–5 |title=Self-consistent electronic structures of MgO and SrO |first1=O.E. |last1=Taurian |doi=10.1016/0038-1098(85)90622-2|last2=Springborg |first2=M. |last3=Christensen |first3=N.E. |issue=4 |url=http://users-phys.au.dk/nec/Papers/necSSC/SSC55351.pdf|bibcode = 1985SSCom..55..351T }}</ref>
| Dipole = 6.2 ± 0.6 D
}}
|Section3={{Chembox Structure
| CrystalStruct = [[Halite]] (cubic), [[Pearson symbol|cF8]]
| SpaceGroup = Fm<u style="text-decoration:overline">3</u>m, No. 225
| Coordination = Octahedral (Mg<sup>2+</sup>); octahedral (O<sup>2−</sup>)
| LattConst_a = 4.212Å
}}
|Section4={{Chembox Thermochemistry
| DeltaHf = −601.8&nbsp;kJ·mol<sup>−1</sup><ref name=b1>{{cite book |last=Zumdahl |first=Steven S. |title=Chemical Principles |edition=6th |publisher=Houghton Mifflin Company |year=2009 |isbn=0-618-94690-X |page=A22}}</ref>
| DeltaGf = -596.6 kJ/mol
| Entropy = 26.9&nbsp;J·mol<sup>−1</sup>·K<sup>−1</sup><ref name=b1/>
| HeatCapacity = 37.8 J/mol K
}}
|Section5={{Chembox Hazards
| ExternalMSDS = [http://www.inchem.org/documents/icsc/icsc/eics0504.htm ICSC 0504]
| EUIndex = Not listed
| EUClass =
| RPhrases = {{R36}}, {{R37}}, {{R38}}
| SPhrases =
| MainHazards = [[Metal fume fever]], Irritant
| NFPA-H = 1
| NFPA-F = 0
| NFPA-R = 0
| NFPA-O =
| FlashPt = Non-flammable
| LD50 =
| PEL = TWA 15 mg/m<sup>3</sup> (fume)<ref name=PGCH/>
| REL = None designated<ref name=PGCH/>
| IDLH = 750 mg/m<sup>3</sup> (fume)<ref name=PGCH>{{PGCH|0374}}</ref>
}}
|Section6={{Chembox Related
| OtherAnions = [[Magnesium sulfide]]
| OtherCations = [[Beryllium oxide]]<br/>[[Calcium oxide]]<br/>[[Strontium oxide]]<br/>[[Barium oxide]]
| OtherFunctn =
| Function =
| OtherCpds = [[Magnesium hydroxide]]<br/>[[Magnesium nitride]]
}}
}}
 
 
 
<!--Mechanism of Action-->
|mechAction=*  
|mechAction=*  


Line 190: Line 259:
|howSupplied=* do not use if imprinted safety seal under cap is broken or missing  
|howSupplied=* do not use if imprinted safety seal under cap is broken or missing  
* Magnesium content per tablet: 240 mg
* Magnesium content per tablet: 240 mg
|storage=store at room temperature 59°-86° F (15°-30°C)  
|storage=store at room temperature 59°-86° F (15°-30°C)
|packLabel=PRINCIPAL DISPLAY PANEL
|packLabel=PRINCIPAL DISPLAY PANEL
: [[File:Magnesium PDP.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
: [[File:Magnesium PDP.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]

Revision as of 13:53, 23 April 2015

Magnesium oxide
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rabin Bista, M.B.B.S. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Magnesium oxide is a antacid that is FDA approved for the treatment of acid indigestion, upset stomach. Common adverse reactions include diarrhea, allergic reaction.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Indications

  • Relieves: acid indigestion, upset stomach

Directions

Antacid Directions: (take 1 tablet twice a day or as directed by a physician

Magnesium Supplement Directions: (take 1 to 2 tablets daily or as directed by a physician

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Magnesium oxide in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Magnesium oxide in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

  • Safety and efficacy in pediatrics patients has not been established.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Magnesium oxide in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Magnesium oxide in pediatric patients.

Contraindications

There is limited information regarding Magnesium oxide Contraindications in the drug label.

Warnings

Do Not Use Do not take more than 2 tablets in a 24 hour period or use the maximum dosage of this product for more than two weeks, except under the advice and supervision of a physician. May have a laxative effect.

Ask a Doctor if you have: Kidney disease

Ask a Doctor/Pharmacist before use if you are: Taking a prescription drug. Antacids may interact with certain prescription drugs.

Pregnancy or Breast Feeding If pregnant or breast feeding, ask a health professional before use.

Keep Out of Reach of Children

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Magnesium oxide in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Postmarketing Experience

Laxative adverse reaction

Drug Interactions

There is limited information regarding Magnesium oxide Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • If pregnant or breast feeding, ask a health professional before use.


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Magnesium oxide in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Magnesium oxide during labor and delivery.

Nursing Mothers

If pregnant or breast feeding, ask a health professional before use.

Pediatric Use

There is no FDA guidance on the use of Magnesium oxide with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Magnesium oxide with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Magnesium oxide with respect to specific gender populations.

Race

There is no FDA guidance on the use of Magnesium oxide with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Magnesium oxide in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Magnesium oxide in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Magnesium oxide in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Magnesium oxide in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral

Monitoring

There is limited information regarding Monitoring of Magnesium oxide in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Magnesium oxide in the drug label.

Overdosage

There is limited information regarding Chronic Overdose of Magnesium oxide in the drug label.

Pharmacology

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox ECNumberTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox AppearanceTemplate:Chembox OdourTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox BandGapTemplate:Chembox ThermalConductivityTemplate:Chembox RefractIndexTemplate:Chembox DipoleTemplate:Chembox StructureTemplate:Chembox ThermochemistryTemplate:Chembox MainHazardsTemplate:Chembox RPhrasesTemplate:Chembox NFPATemplate:Chembox FlashPtTemplate:Chembox NIOSH (set)Template:Chembox OtherAnionsTemplate:Chembox OtherCationsTemplate:Chembox Supplement
Template:Chembox header2 | Magnesium oxide
Identifiers
ChEMBL
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
Properties
MgO
Molar mass 40.3044 g/mol
Hazards
Related compounds
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Mechanism of Action

Structure

  • ACTIVE INGREDIENTS

Magnesium Oxide 400mg (241.3mg elemental magnesium)

INACTIVE INGREDIENTS Colloidal silicon dioxide, croscarmellose sodium, microcrystalline cellulose, stearic acid

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Magnesium oxide in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Magnesium oxide in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Magnesium oxide in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Magnesium oxide in the drug label.

How Supplied

  • do not use if imprinted safety seal under cap is broken or missing
  • Magnesium content per tablet: 240 mg

Storage

store at room temperature 59°-86° F (15°-30°C)

Images

Drug Images

{{#ask: Page Name::Magnesium oxide |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

PRINCIPAL DISPLAY PANEL

This image is provided by the National Library of Medicine.

Ingredients and Appearance

This image is provided by the National Library of Medicine.

{{#ask: Label Page::Magnesium oxide |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Magnesium oxide in the drug label.

Precautions with Alcohol

  • Alcohol-Magnesium oxide interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

There is limited information regarding look alike drug names.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Taurian, O.E.; Springborg, M.; Christensen, N.E. (1985). "Self-consistent electronic structures of MgO and SrO" (PDF). Solid State Communications. 55 (4): 351–5. Bibcode:1985SSCom..55..351T. doi:10.1016/0038-1098(85)90622-2.
  2. ↑ Application of magnesium compounds to insulating heat-conductive fillers. konoshima.co.jp
  3. ↑ 3.0 3.1 3.2 Template:PGCH
  4. ↑ "Magnesium oxide".

{{#subobject: 

 |Page Name=Magnesium oxide
 |Pill Name=No image.jpg
 |Drug Name=
 |Pill Ingred=|+sep=;
 |Pill Imprint=
 |Pill Dosage={{{dosageValue}}} {{{dosageUnit}}}
 |Pill Color=|+sep=;
 |Pill Shape=
 |Pill Size (mm)=
 |Pill Scoring=
 |Pill Image=
 |Drug Author=
 |NDC=

}}

{{#subobject: 

 |Label Page=Magnesium oxide
 |Label Name=Magnesium oxide11.png

}}

{{#subobject: 

 |Label Page=Magnesium oxide
 |Label Name=Magnesium oxide11.png

}}

Retrieved from "https://www.wikidoc.org/index.php?title=Magnesium_oxide&oldid=1090826"