MYH2

Myosin, heavy chain 2, skeletal muscle, adult
Identifiers
Symbols	MYH2 ; MYH2A; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa
External IDs	Template:OMIM5 Template:MGI HomoloGene: 75068
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE MYH2 204631 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Myosin, heavy chain 2, skeletal muscle, adult, also known as MYH2, is a human gene.

Further reading

• Schwartz CE, McNally E, Leinwand L, Skolnick MH (1987). "A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13". Cytogenet. Cell Genet. 43 (1–2): 117–20. PMID 2877813.CS1 maint: Multiple names: authors list (link)
• Smerdu V, Karsch-Mizrachi I, Campione M; et al. (1995). "Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle". Am. J. Physiol. 267 (6 Pt 1): C1723–8. PMID 7545970.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ennion S, Sant'ana Pereira J, Sargeant AJ; et al. (1995). "Characterization of human skeletal muscle fibres according to the myosin heavy chains they express". J. Muscle Res. Cell. Motil. 16 (1): 35–43. PMID 7751403.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hisatome I, Morisaki T, Kamma H; et al. (1998). "Control of AMP deaminase 1 binding to myosin heavy chain". Am. J. Physiol. 275 (3 Pt 1): C870–81. PMID 9730972.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weiss A, McDonough D, Wertman B; et al. (1999). "Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved". Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2958–63. PMID 10077619.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weiss A, Schiaffino S, Leinwand LA (1999). "Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity". J. Mol. Biol. 290 (1): 61–75. doi:10.1006/jmbi.1999.2865. PMID 10388558.CS1 maint: Multiple names: authors list (link)
• Onuoha GN, Alpar EK, Laprade M; et al. (1999). "Effects of bone fracture and surgery on plasma myosin heavy chain fragments of skeletal muscle". Clinical and investigative medicine. Médecine clinique et experimentale. 22 (5): 180–4. PMID 10579056.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Martinsson T, Oldfors A, Darin N; et al. (2001). "Autosomal dominant myopathy: missense mutation (Glu-706 --> Lys) in the myosin heavy chain IIa gene". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14614–9. doi:10.1073/pnas.250289597. PMID 11114175.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tajsharghi H, Thornell LE, Darin N; et al. (2002). "Myosin heavy chain IIa gene mutation E706K is pathogenic and its expression increases with age". Neurology. 58 (5): 780–6. PMID 11889243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• England K, Ashford D, Kidd D, Rumsby M (2002). "PKC epsilon is associated with myosin IIA and actin in fibroblasts". Cell. Signal. 14 (6): 529–36. PMID 11897493.CS1 maint: Multiple names: authors list (link)
• Allen DL, Leinwand LA (2003). "Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter". J. Biol. Chem. 277 (47): 45323–30. doi:10.1074/jbc.M208302200. PMID 12235157.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim EJ, Helfman DM (2003). "Characterization of the metastasis-associated protein, S100A4. Roles of calcium binding and dimerization in cellular localization and interaction with myosin". J. Biol. Chem. 278 (32): 30063–73. doi:10.1074/jbc.M304909200. PMID 12756252.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chung MC, Kawamoto S (2005). "IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression during phorbol ester-induced promyelocytic HL-60 differentiation". J. Biol. Chem. 279 (53): 56042–52. doi:10.1074/jbc.M404791200. PMID 15496418.
• Tajsharghi H, Darin N, Rekabdar E; et al. (2005). "Mutations and sequence variation in the human myosin heavy chain IIa gene (MYH2)". Eur. J. Hum. Genet. 13 (5): 617–22. doi:10.1038/sj.ejhg.5201375. PMID 15741996.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Li M, Lionikas A, Yu F; et al. (2006). "Muscle cell and motor protein function in patients with a IIa myosin missense mutation (Glu-706 to Lys)". Neuromuscul. Disord. 16 (11): 782–91. doi:10.1016/j.nmd.2006.07.023. PMID 17005402.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)