Lymphangioma diagnostic study of choice

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Overview

Diagnostic Study of Choice

Study of choice:

  • MRI is the gold standard test for the diagnosis of lymphangioma.[1]
  • MRI can mar the degree of involvement and extent of lesion.
  • MRI can prevent extensive, incomplete surgical resection, because poorly removed lesion can lead to recurrence.

Biopsy:

Biopsy is used to analyze the structure of tissue. It shows[2][3]

  • Dilated lymph channels ultimately causes the papillary dermis to expand.
  • THese channels extend to subcutis.
  • Deeper vessels have larger lumen and muscular coat.
  • The lumen has lymphatic fluid, but it often contains red blood cells, lymphocytes, macrophages, and neutrophils.
  • These channels re lined by endothelial cells.
  • Numerous lymphoid cells are also seen.

Histochemical staining:

  • Histochemical staining is recommended to document lymphangioma.[4]

Other Tests:

In addition to above, various investigations must be performed in the following order:[5][4][6]

  • Plain radiograph
  • Ultrasound
  • CT scan

References

{reflist|2}

  1. Kennedy TL, Whitaker M, Pellitteri P, Wood WE (November 2001). "Cystic hygroma/lymphangioma: a rational approach to management". Laryngoscope. 111 (11 Pt 1): 1929–37. doi:10.1097/00005537-200111000-00011. PMID 11801972.
  2. WARD GE, HENDRICK JW, CHAMBERS RG (February 1950). "Cystic hygroma of the neck". West J Surg Obstet Gynecol. 58 (2): 41–7, illust. PMID 15402902.
  3. Turki, Ali (2017). "Abdominal Cystic Lymphangioma in Adults: Diagnostic Difficulties and Surgical Outcome". Journal of Universal Surgery. 04 (05). doi:10.21767/2254-6758.100066. ISSN 2254-6758.
  4. 4.0 4.1 Paal, Edina; Thompson, Lester D.; Heffess, Clara S. (1998). "A clinicopathologic and immunohistochemical study of ten pancreatic lymphangiomas and a review of the literature". Cancer. 82 (11): 2150–2158. doi:10.1002/(SICI)1097-0142(19980601)82:11<2150::AID-CNCR9>3.0.CO;2-Z. ISSN 0008-543X.
  5. Park SH, Moon SK, Sung JY (May 2014). "Sonographic findings in a case of scrotal lymphangioma". J Clin Ultrasound. 42 (4): 234–6. doi:10.1002/jcu.22095. PMID 24691940.
  6. Matter D, Grosshans E, Muller J, Furderer C, Mathelin C, Warter S, Bellocq JP, Maillot C (May 2002). "[Sonographic imaging of lymphatic vessels compared to other methods]". J Radiol (in French). 83 (5): 599–609. PMID 12063422.