Leptospirosis (patient information)

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Leptospirosis

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

When to seek urgent medical care?

Diagnosis

Treatment options

Where to find medical care for Leptospirosis?

What to expect (Outlook/Prognosis)?

Possible complications

Prevention

Leptospirosis On the Web

Ongoing Trials at Clinical Trials.gov

Images of Leptospirosis

Videos on Leptospirosis

FDA on Leptospirosis

CDC on Leptospirosis

Leptospirosis in the news

Blogs on Leptospirosis

Directions to Hospitals Treating Leptospirosis

Risk calculators and risk factors for Leptospirosis

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Leptospirosis is a bacterial disease that affects humans and animals. It is caused by bacteria of the genus Leptospira. In humans, it can cause a wide range of symptoms, some of which may be mistaken for other diseases. Some infected persons, however, may have no symptoms at all.

Without treatment, Leptospirosis can lead to kidney damage, meningitis (inflammation of the membrane around the brain and spinal cord), liver failure, respiratory distress, and even death.

What are the symptoms of (disease name)?

In humans, Leptospirosis can cause a wide range of symptoms, including:

  • High fever
  • Headache
  • Chills
  • Muscle aches
  • Vomiting
  • Jaundice (yellow skin and eyes)
  • Red eyes
  • Abdominal pain
  • Diarrhea
  • Rash

What causes (disease name)?

Who is at highest risk?

Outbreaks of leptospirosis are usually caused by exposure to water contaminated with the urine of infected animals. Many different kinds of animals carry the bacterium; they may become sick but sometimes have no symptoms. Leptospira organisms have been found in cattle, pigs, horses, dogs, rodents, and wild animals. Humans become infected through contact with water, food, or soil containing urine from these infected animals. This may happen by swallowing contaminated food or water or through skin contact, especially with mucosal surfaces, such as the eyes or nose, or with broken skin. The disease is not known to be spread from person to person.

Diagnosis

When to seek urgent medical care?

The time between a person's exposure to a contaminated source and becoming sick is 2 days to 4 weeks. Illness usually begins abruptly with fever and other symptoms. Leptospirosis may occur in two phases; after the first phase, with fever, chills, headache, muscle aches, vomiting, or diarrhea, the patient may recover for a time but become ill again. If a second phase occurs, it is more severe; the person may have kidney or liver failure or meningitis. This phase is also called Weil's disease.

The illness lasts from a few days to 3 weeks or longer. Without treatment, recovery may take several months.

Treatment options

Leptospirosis is treated with antibiotics, such as doxycycline or penicillin, which should be given early in the course of the disease.

Intravenous antibiotics may be required for persons with more severe symptoms. Persons with symptoms suggestive of leptospirosis should contact a health care provider.

Where to find medical care for (disease name)?

Prevention

The risk of acquiring leptospirosis can be greatly reduced by not swimming or wading in water that might be contaminated with animal urine. Protective clothing or footwear should be worn by those exposed to contaminated water or soil because of their job or recreational activities.

What to expect (Outlook/Prognosis)?

Possible complications

Sources

http://www.cdc.gov/leptospirosis/

http://www.who.int/topics/leptospirosis/en/