Laryngitis medical therapy: Difference between revisions
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===Antibiotic Therapy=== | ===Antibiotic Therapy=== | ||
* Antibiotic use is not associated with significant improvement of objective symptoms<ref name="Reveiz-2005">{{Cite journal | last1 = Reveiz | first1 = L. | last2 = Cardona | first2 = AF. | last3 = Ospina | first3 = EG. | title = Antibiotics for acute laryngitis in adults. | journal = Cochrane Database Syst Rev | volume = | issue = 1 | pages = CD004783 | month = | year = 2005 | doi = 10.1002/14651858.CD004783.pub2 | PMID = 15674965 }}</ref><ref name="Reveiz-2007">{{Cite journal | last1 = Reveiz | first1 = L. | last2 = Cardona | first2 = AF. | last3 = Ospina | first3 = EG. | title = Antibiotics for acute laryngitis in adults. | journal = Cochrane Database Syst Rev | volume = | issue = 2 | pages = CD004783 | month = | year = 2007 | doi = 10.1002/14651858.CD004783.pub3 | PMID = 17443555 }}</ref><ref name="Reveiz-2013">{{Cite journal | last1 = Reveiz | first1 = L. | last2 = Cardona | first2 = AF. | title = Antibiotics for acute laryngitis in adults. | journal = Cochrane Database Syst Rev | volume = 3 | issue = | pages = CD004783 | month = | year = 2013 | doi = 10.1002/14651858.CD004783.pub4 | PMID = 23543536 }}</ref> and is not | * Antibiotic use is not associated with significant improvement of objective symptoms<ref name="Reveiz-2005">{{Cite journal | last1 = Reveiz | first1 = L. | last2 = Cardona | first2 = AF. | last3 = Ospina | first3 = EG. | title = Antibiotics for acute laryngitis in adults. | journal = Cochrane Database Syst Rev | volume = | issue = 1 | pages = CD004783 | month = | year = 2005 | doi = 10.1002/14651858.CD004783.pub2 | PMID = 15674965 }}</ref><ref name="Reveiz-2007">{{Cite journal | last1 = Reveiz | first1 = L. | last2 = Cardona | first2 = AF. | last3 = Ospina | first3 = EG. | title = Antibiotics for acute laryngitis in adults. | journal = Cochrane Database Syst Rev | volume = | issue = 2 | pages = CD004783 | month = | year = 2007 | doi = 10.1002/14651858.CD004783.pub3 | PMID = 17443555 }}</ref><ref name="Reveiz-2013">{{Cite journal | last1 = Reveiz | first1 = L. | last2 = Cardona | first2 = AF. | title = Antibiotics for acute laryngitis in adults. | journal = Cochrane Database Syst Rev | volume = 3 | issue = | pages = CD004783 | month = | year = 2013 | doi = 10.1002/14651858.CD004783.pub4 | PMID = 23543536 }}</ref> and is not a first-line therapy for the treatment of acute laryngitis.<ref name="Schwartz-2009">{{Cite journal | last1 = Schwartz | first1 = SR. | last2 = Cohen | first2 = SM. | last3 = Dailey | first3 = SH. | last4 = Rosenfeld | first4 = RM. | last5 = Deutsch | first5 = ES. | last6 = Gillespie | first6 = MB. | last7 = Granieri | first7 = E. | last8 = Hapner | first8 = ER. | last9 = Kimball | first9 = CE. | title = Clinical practice guideline: hoarseness (dysphonia). | journal = Otolaryngol Head Neck Surg | volume = 141 | issue = 3 Suppl 2 | pages = S1-S31 | month = Sep | year = 2009 | doi = 10.1016/j.otohns.2009.06.744 | PMID = 19729111 }}</ref> | ||
* [[Penicillin V]] and [[erythromycin]] may be used; however, they were only shown to be effective using subjective measures. | * [[Penicillin V]] and [[erythromycin]] may be used; however, they were only shown to be effective using subjective measures. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2], Alonso Alvarado, M.D. [3]
Overview
Patients with viral laryngitis are treated with supportive therapy, whereas patients with laryngitis due to infectious causes other than viral infections are treated with antimicrobial therapy. Medical therapy for laryngitis due to gastroesophageal reflux includes acid suppression therapy such as either omeprazole or ranitidine . Surgery is usually reserved for patients with persistent laryngitis due to vocal cord nodules.
Medical Therapy
- Correct treatment depends on a correct diagnosis of the underlying cause of laryngitis.
- The most prevalent cause of a missed diagnosis of laryngeal cancer is a belief that persistent hoarseness is due to laryngitis.
- Should hoarseness last for more than 3 weeks, one should consult an otolaryngologist for an examination including direct visualization of the vocal cords. This examination may also detect the presence of vocal cord nodules.
If laryngitisis due to a viral cause:
- Ibuprofen and aspirin may help alleviate fever and some of the discomfort associated with laryngitis.
- Patients are advised to avoid speaking when possible. They are instructed to speak softly, but to avoid whispering, which further strains the voice.[1]
- Throat clearing is not advised. The act of clearing one's throat may aggravate the laryngitis.
- Airborne irritants such as smoke and allergens may exacerbate the condition.
- Mouth rinses containing alcohol can dry the throat and may exacerbate a viral case of laryngitis. However, these can be helpful when the cause of the infection is bacterial.
- Humidifiers and warm showers can also help alleviate some symptoms.
- Steroids may be prescribed to help accelerate the healing if significant inflammation is present.
If laryngitis is due to gastroesophageal reflux:
- An H2-antagonist (e.g.: ranitidine) or a proton-pump inhibitor (PPI) (e.g.: omeprazole, esomeprazole, pantoprazole) may be prescribed for a period of 4-6 weeks.
If laryngitis is due to a bacterial organism:
- The patient may be prescribed a course of antibiotics however, there is little evidence to demonstrates the efficacy of oral antibiotics for laryngitis.
If persistent hoarseness or loss of voice is a result of vocal cord nodules:
- Surgical resection of the nodule and/or speech therapy may be recommended.
- Reduction of high-impact stress to the vocal cords caused by loud, frequent, and rapid speech is recommended.
Antibiotic Therapy
- Antibiotic use is not associated with significant improvement of objective symptoms[2][3][4] and is not a first-line therapy for the treatment of acute laryngitis.[5]
- Penicillin V and erythromycin may be used; however, they were only shown to be effective using subjective measures.
- Fusafungine, a locally acting antibiotic, has been shown to increase the number of asymptomatic patients by the fifth day of disease.
References
- ↑ Mayoclinic.com. 2006. Laryngitis: Self care
- ↑ Reveiz, L.; Cardona, AF.; Ospina, EG. (2005). "Antibiotics for acute laryngitis in adults". Cochrane Database Syst Rev (1): CD004783. doi:10.1002/14651858.CD004783.pub2. PMID 15674965.
- ↑ Reveiz, L.; Cardona, AF.; Ospina, EG. (2007). "Antibiotics for acute laryngitis in adults". Cochrane Database Syst Rev (2): CD004783. doi:10.1002/14651858.CD004783.pub3. PMID 17443555.
- ↑ Reveiz, L.; Cardona, AF. (2013). "Antibiotics for acute laryngitis in adults". Cochrane Database Syst Rev. 3: CD004783. doi:10.1002/14651858.CD004783.pub4. PMID 23543536.
- ↑ Schwartz, SR.; Cohen, SM.; Dailey, SH.; Rosenfeld, RM.; Deutsch, ES.; Gillespie, MB.; Granieri, E.; Hapner, ER.; Kimball, CE. (2009). "Clinical practice guideline: hoarseness (dysphonia)". Otolaryngol Head Neck Surg. 141 (3 Suppl 2): S1–S31. doi:10.1016/j.otohns.2009.06.744. PMID 19729111. Unknown parameter
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