Lanoxin tablet/pediatric indications and dosage: Difference between revisions

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__NOTOC__
{{Lanoxin tablet}}
{{CMG}};{{AE}} {{AK}}
===Heart failure===
===Heart failure===


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0.01 mg/kg orally 3 times daily for the first 2 doses, then 0.0035 mg/kg 3 times daily<ref name="Pfammatter-1998">{{Cite journal  | last1 = Pfammatter | first1 = JP. | last2 = Stocker | first2 = FP. | title = Re-entrant supraventricular tachycardia in infancy: current role of prophylactic digoxin treatment. | journal = Eur J Pediatr | volume = 157 | issue = 2 | pages = 101-6 | month = Feb | year = 1998 | doi =  | PMID = 9504781 }}</ref><ref name="Sanatani-2012">{{Cite journal  | last1 = Sanatani | first1 = S. | last2 = Potts | first2 = JE. | last3 = Reed | first3 = JH. | last4 = Saul | first4 = JP. | last5 = Stephenson | first5 = EA. | last6 = Gibbs | first6 = KA. | last7 = Anderson | first7 = CC. | last8 = Mackie | first8 = AS. | last9 = Ro | first9 = PS. | title = The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants. | journal = Circ Arrhythm Electrophysiol | volume = 5 | issue = 5 | pages = 984-91 | month = Oct | year = 2012 | doi = 10.1161/CIRCEP.112.972620 | PMID = 22962431 }}</ref>
0.01 mg/kg orally 3 times daily for the first 2 doses, then 0.0035 mg/kg 3 times daily<ref name="Pfammatter-1998">{{Cite journal  | last1 = Pfammatter | first1 = JP. | last2 = Stocker | first2 = FP. | title = Re-entrant supraventricular tachycardia in infancy: current role of prophylactic digoxin treatment. | journal = Eur J Pediatr | volume = 157 | issue = 2 | pages = 101-6 | month = Feb | year = 1998 | doi =  | PMID = 9504781 }}</ref><ref name="Sanatani-2012">{{Cite journal  | last1 = Sanatani | first1 = S. | last2 = Potts | first2 = JE. | last3 = Reed | first3 = JH. | last4 = Saul | first4 = JP. | last5 = Stephenson | first5 = EA. | last6 = Gibbs | first6 = KA. | last7 = Anderson | first7 = CC. | last8 = Mackie | first8 = AS. | last9 = Ro | first9 = PS. | title = The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants. | journal = Circ Arrhythm Electrophysiol | volume = 5 | issue = 5 | pages = 984-91 | month = Oct | year = 2012 | doi = 10.1161/CIRCEP.112.972620 | PMID = 22962431 }}</ref>
====Fetal tachycardia - Supraventricular tachycardia====
====Fetal tachycardia - Supraventricular tachycardia====
Maternal 0.25 to 0.375 mg PO daily alone or with [[verapamil]].<ref name="Lilja-1984">{{Cite journal  | last1 = Lilja | first1 = H. | last2 = Karlsson | first2 = K. | last3 = Lindecrantz | first3 = K. | last4 = Sabel | first4 = KG. | title = Treatment of intrauterine supraventricular tachycardia with digoxin and verapamil. | journal = J Perinat Med | volume = 12 | issue = 3 | pages = 151-4 | month =  | year = 1984 | doi =  | PMID = 6502442 }}</ref>
{{DrugReflist}}
{{DrugReflist}}

Revision as of 16:19, 20 March 2014

Lanoxin tablet®
Black Box Warning
Adult Indications and Dosage
Pediatric Indications and Dosage
Contraindications
Warnings
Adverse Reactions
Drug Interactions
Use in Specific Populations
Routes and Preparations
IV Compatibility
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Information
Combined Alcohol Use
Look-Alike Drug Names
Drug Shortage Status
Price

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]

Heart failure

Loading dose:

5-10 years old 20-45 mcg/kg Administer half the total loading dose initially,

then ¼ the loading dose every 6 to 8 hours twice.

>10 year old 10-15 mcg/kg Administer half the total loading dose initially, then ¼ the loading dose every 6 to 8 hours twice.

Maintenence dose:

Less than 10 years 3.2-6.4 mcg/kg/dose twice a day.

More than 10 years 3.4-5.1 mcg/kg/day

Off-Label Use (Pediatric)

Supraventricular tachycardia, Recurrent; Prophylaxis

0.01 mg/kg orally 3 times daily for the first 2 doses, then 0.0035 mg/kg 3 times daily[1][2]

Fetal tachycardia - Supraventricular tachycardia

Maternal 0.25 to 0.375 mg PO daily alone or with verapamil.[3]


References

  1. Pfammatter, JP.; Stocker, FP. (1998). "Re-entrant supraventricular tachycardia in infancy: current role of prophylactic digoxin treatment". Eur J Pediatr. 157 (2): 101–6. PMID 9504781. Unknown parameter |month= ignored (help)
  2. Sanatani, S.; Potts, JE.; Reed, JH.; Saul, JP.; Stephenson, EA.; Gibbs, KA.; Anderson, CC.; Mackie, AS.; Ro, PS. (2012). "The study of antiarrhythmic medications in infancy (SAMIS): a multicenter, randomized controlled trial comparing the efficacy and safety of digoxin versus propranolol for prophylaxis of supraventricular tachycardia in infants". Circ Arrhythm Electrophysiol. 5 (5): 984–91. doi:10.1161/CIRCEP.112.972620. PMID 22962431. Unknown parameter |month= ignored (help)
  3. Lilja, H.; Karlsson, K.; Lindecrantz, K.; Sabel, KG. (1984). "Treatment of intrauterine supraventricular tachycardia with digoxin and verapamil". J Perinat Med. 12 (3): 151–4. PMID 6502442.