KIF3B

Kinesin family member 3B
Identifiers
Symbols	KIF3B ; HH0048; KIAA0359
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55849
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE KIF3B 203943 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Kinesin family member 3B, also known as KIF3B, is a human gene.

The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.

Further reading

• Yamazaki H, Nakata T, Okada Y, Hirokawa N (1995). "KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport". J. Cell Biol. 130 (6): 1387–99. PMID 7559760.CS1 maint: Multiple names: authors list (link)
• Nagase T, Ishikawa K, Nakajima D; et al. (1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. PMID 9205841.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagata K, Puls A, Futter C; et al. (1998). "The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3". EMBO J. 17 (1): 149–58. doi:10.1093/emboj/17.1.149. PMID 9427749.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shimizu K, Shirataki H, Honda T; et al. (1998). "Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide". J. Biol. Chem. 273 (12): 6591–4. PMID 9506951.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nonaka S, Tanaka Y, Okada Y; et al. (1999). "Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein". Cell. 95 (6): 829–37. PMID 9865700.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Navarro E, Espinosa L, Adell T; et al. (1999). "Expressed sequence tag (EST) phenotyping of HT-29 cells: cloning of ser/thr protein kinase EMK1, kinesin KIF3B, and of transcripts that include Alu repeated elements". Biochim. Biophys. Acta. 1450 (3): 254–64. PMID 10395937.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Whitehead JL, Wang SY, Bost-Usinger L; et al. (1999). "Photoreceptor localization of the KIF3A and KIF3B subunits of the heterotrimeric microtubule motor kinesin II in vertebrate retina". Exp. Eye Res. 69 (5): 491–503. doi:10.1006/exer.1999.0724. PMID 10548469.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Deloukas P, Matthews LH, Ashurst J; et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jimbo T, Kawasaki Y, Koyama R; et al. (2002). "Identification of a link between the tumour suppressor APC and the kinesin superfamily". Nat. Cell Biol. 4 (4): 323–7. doi:10.1038/ncb779. PMID 11912492.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Baker SA, Freeman K, Luby-Phelps K; et al. (2003). "IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia". J. Biol. Chem. 278 (36): 34211–8. doi:10.1074/jbc.M300156200. PMID 12821668.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Imamura T, Huang J, Usui I; et al. (2003). "Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin". Mol. Cell. Biol. 23 (14): 4892–900. PMID 12832475.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang Y, Hancock WO (2005). "The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds". Biophys. J. 87 (3): 1795–804. doi:10.1529/biophysj.104.039842. PMID 15345558.
• Haraguchi K, Hayashi T, Jimbo T; et al. (2006). "Role of the kinesin-2 family protein, KIF3, during mitosis". J. Biol. Chem. 281 (7): 4094–9. doi:10.1074/jbc.M507028200. PMID 16298999.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wu Y, Dai XQ, Li Q; et al. (2006). "Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin". Hum. Mol. Genet. 15 (22): 3280–92. doi:10.1093/hmg/ddl404. PMID 17008358.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)