Isopropyl alcohol: Difference between revisions

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{{DrugProjectFormSinglePage
{{DrugProjectFormSinglePage
|authorTag=<!--Overview-->
|authorTag={{Ammu}}
|genericName=topical antimicrobial
|aOrAn=a
|aOrAn=a
|hasBlackBoxWarning=Yes
|drugClass=antiseptic
|adverseReactions=<!--Black Box Warning-->
|indicationType=treatment
|indication=cuts, scrapes and minor muscular aches
|adverseReactions=hypersensitivity
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>
Line 12: Line 15:


<!--FDA-Labeled Indications and Dosage (Adult)-->
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult======Condition1=====
|fdaLIADAdult=to decrease germs in minor cuts and scrapes.
helps relieve minor muscular aches due to exertion.


* Dosing Information
|offLabelAdultGuideSupport=


:* Dosage


=====Condition2=====
* Dosing Information
:* Dosage
=====Condition3=====
* Dosing Information
:* Dosage
=====Condition4=====
* Dosing Information
:* Dosage
<!--Off-Label Use and Dosage (Adult)-->
<!--Guideline-Supported Use (Adult)-->
|offLabelAdultGuideSupport======Condition1=====
* Developed by:
* Class of Recommendation:
* Strength of Evidence:
* Dosing Information
:* Dosage
=====Condition2=====


There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.


<!--Non–Guideline-Supported Use (Adult)-->
<!--Non–Guideline-Supported Use (Adult)-->
|offLabelAdultNoGuideSupport======Condition1=====
|offLabelAdultNoGuideSupport=
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====


There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
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<!--FDA-Labeled Indications and Dosage (Pediatric)-->
<!--FDA-Labeled Indications and Dosage (Pediatric)-->
|fdaLIADPed======Condition1=====
|fdaLIADPed=
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====


There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
There is limited information regarding <i>FDA-Labeled Use</i> of {{PAGENAME}} in pediatric patients.
Line 82: Line 39:


<!--Guideline-Supported Use (Pediatric)-->
<!--Guideline-Supported Use (Pediatric)-->
|offLabelPedGuideSupport======Condition1=====
|offLabelPedGuideSupport=
 
* Developed by:
 
* Class of Recommendation:
 
* Strength of Evidence:
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====
 
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.


<!--Non–Guideline-Supported Use (Pediatric)-->
<!--Non–Guideline-Supported Use (Pediatric)-->
|offLabelPedNoGuideSupport======Condition1=====
|offLabelPedNoGuideSupport=
 
* Dosing Information
 
:* Dosage
 
=====Condition2=====


There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.


<!--Contraindications-->
<!--Contraindications-->
|contraindications=* Condition1
|warnings=* For external use only
 
<!--Warnings-->
|warnings=* Description


====Precautions====
flammable, keep away from fire and flame
will produce serious gastric disturbances if taken internally
Ask a doctor before use if you have deep puncture wounds or serious burns
When using this product


* Description
do not get into eyes or mucous membranes
 
use only in a well-ventilated area
<!--Adverse Reactions-->
Stop use and ask a doctor if condition persists or gets worse.
 
Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately.
<!--Clinical Trials Experience-->
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|clinicalTrials=There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.


=====Body as a Whole=====


=====Cardiovascular=====
=====Digestive=====
=====Endocrine=====
=====Hematologic and Lymphatic=====
=====Metabolic and Nutritional=====
=====Musculoskeletal=====
=====Neurologic=====
=====Respiratory=====
=====Skin and Hypersensitivy Reactions=====
=====Special Senses=====
=====Urogenital=====
=====Miscellaneous=====
<!--Postmarketing Experience-->
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
=====Body as a Whole=====
=====Cardiovascular=====
=====Digestive=====
=====Endocrine=====
=====Hematologic and Lymphatic=====
=====Metabolic and Nutritional=====




=====Musculoskeletal=====
=====Neurologic=====
=====Respiratory=====
=====Skin and Hypersensitivy Reactions=====
=====Special Senses=====
=====Urogenital=====
=====Miscellaneous=====
<!--Drug Interactions-->
|drugInteractions=* Drug
|drugInteractions=* Drug
:* Description
:* Description
Line 264: Line 85:


<!--Administration and Monitoring-->
<!--Administration and Monitoring-->
|administration=* Oral
|administration=* Topical
 
* Intravenous
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.
|monitoring=There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.


* Description
<!--IV Compatibility-->
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
|IVCompat=There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.


<!--Overdosage-->
<!--Overdosage-->
|overdose====Acute Overdose===
|drugBox=* {{chembox2
 
| Watchedfields = changed
====Signs and Symptoms====
| verifiedrevid = 477002700
 
|  Name = Isopropyl alcohol
* Description
|  ImageFileL1 = 2-Propanol.svg
 
|  ImageNameL1 = Skeletal formula of isopropyl alcohol
====Management====
|  ImageFileR1 = Propan-2-ol-3D-balls.png
 
|  ImageNameR1 = Ball-and-stick model of isopropyl alcohol
* Description
|  PIN = 2-Propanol
 
|  IUPACName =isopropyl alcohol
===Chronic Overdose===
|  OtherNames = Propan-2-ol; Isopropanol; [[Rubbing alcohol]]; ''sec''-Propyl alcohol; ''s''-Propanol; iPrOH; IPA
 
| Section1 = {{Chembox Identifiers
There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.
|  ChEBI_Ref = {{ebicite|correct|EBI}}
 
| ChEBI = 17824
<!--Pharmacology-->
| SMILES = CC(O)C
 
| UNII_Ref = {{fdacite|correct|FDA}}
<!--Drug box 2-->
| UNII = ND2M416302
|drugBox=<!--Mechanism of Action-->
| UNNumber = 1219
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 582
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = KFZMGEQAYNKOFK-UHFFFAOYSA-N
| CASNo = 67-63-0
| CASNo_Ref = {{cascite|correct|CAS}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 3644
| PubChem = 3776
| RTECS = NT8050000
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00137
| ATCCode_prefix = D08
| ATCCode_suffix = AX05
  }}
| Section2 = {{Chembox Properties
|  C=3|H=8|O=1
|  Appearance = Colorless liquid
|  Density = 0.786 g/cm<sup>3</sup> (20 °C)
|  Solubility = [[miscible]]
|  SolubleOther = miscible in [[benzene]], [[chloroform]], [[ethanol]], [[ether]], [[glycerin]] <br> soluble in [[acetone]] <br> insoluble in [[salt]] solutions
|  MeltingPtC = −89
|  BoilingPtC = 82.6
|  pKa = 16.5<ref>{{cite journal|author=Reeve, W.; Erikson, C.M.; Aluotto, P.F. |journal=Can. J. Chem.|year=1979|volume=57|issue=20|pages= 2747|doi=10.1139/v79-444|title=A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides}}</ref>
|   Viscosity = 2.86 c[[Poise|P]] at 15 °C<br>1.96 c[[Poise|P]] at 25 °C<ref name = yaws>{{cite book | title = Chemical Properties Handbook | author = Yaws, C.L. | publisher = [[McGraw-Hill]] | year = 1999 | isbn = 0-07-073401-1}}</ref><br>1.77 c[[Poise|P]] at 30 °C<ref name = yaws/>
|  Dipole = 1.66 [[Debye|D]] (gas)
|  RefractIndex = 1.3776
  }}
|mechAction=*  
|mechAction=*  


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|howSupplied=*
|howSupplied=*
|packLabel=<!--Patient Counseling Information-->
|packLabel=<!--Patient Counseling Information-->
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of {{PAGENAME}} in the drug label.
|fdaPatientInfo=apply to skin directly or with clean gauze, cotton or swab.
for rubbing, apply liberally and rub with hands.


<!--Precautions with Alcohol-->
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.


<!--Brand Names-->
<!--Brand Names-->
|brandNames=* ®<ref>{{Cite web | title = | url = }}</ref>
|brandNames=* ISOPROPYL RUBBING ALCOHOL®<ref>{{Cite web | title =ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid  | url = http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ff80a29c-ed8b-4aa2-badf-f8d11172e52d}}</ref>


<!--Look-Alike Drug Names-->
<!--Look-Alike Drug Names-->

Revision as of 21:44, 28 January 2015

{{DrugProjectFormSinglePage |authorTag=Ammu Susheela, M.D. [1] |genericName=topical antimicrobial |aOrAn=a |drugClass=antiseptic |indicationType=treatment |indication=cuts, scrapes and minor muscular aches |adverseReactions=hypersensitivity |blackBoxWarningTitle=ConditionName: |blackBoxWarningBody=ConditionName:

  • Content


|fdaLIADAdult=to decrease germs in minor cuts and scrapes. helps relieve minor muscular aches due to exertion.

|offLabelAdultGuideSupport=


There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in adult patients.

|offLabelAdultNoGuideSupport=

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in adult patients.


|fdaLIADPed=

There is limited information regarding FDA-Labeled Use of Isopropyl alcohol in pediatric patients.


|offLabelPedGuideSupport= There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

|offLabelPedNoGuideSupport=

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

|warnings=* For external use only

flammable, keep away from fire and flame will produce serious gastric disturbances if taken internally Ask a doctor before use if you have deep puncture wounds or serious burns When using this product

do not get into eyes or mucous membranes use only in a well-ventilated area Stop use and ask a doctor if condition persists or gets worse. Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately. |clinicalTrials=There is limited information regarding Clinical Trial Experience of Isopropyl alcohol in the drug label.


|postmarketing=There is limited information regarding Postmarketing Experience of Isopropyl alcohol in the drug label.


|drugInteractions=* Drug

  • Description

|useInPregnancyFDA=* Pregnancy Category |useInPregnancyAUS=* Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isopropyl alcohol in women who are pregnant. |useInLaborDelivery=There is no FDA guidance on use of Isopropyl alcohol during labor and delivery. |useInNursing=There is no FDA guidance on the use of Isopropyl alcohol with respect to nursing mothers. |useInPed=There is no FDA guidance on the use of Isopropyl alcohol with respect to pediatric patients. |useInGeri=There is no FDA guidance on the use of Isopropyl alcohol with respect to geriatric patients. |useInGender=There is no FDA guidance on the use of Isopropyl alcohol with respect to specific gender populations. |useInRace=There is no FDA guidance on the use of Isopropyl alcohol with respect to specific racial populations. |useInRenalImpair=There is no FDA guidance on the use of Isopropyl alcohol in patients with renal impairment. |useInHepaticImpair=There is no FDA guidance on the use of Isopropyl alcohol in patients with hepatic impairment. |useInReproPotential=There is no FDA guidance on the use of Isopropyl alcohol in women of reproductive potentials and males. |useInImmunocomp=There is no FDA guidance one the use of Isopropyl alcohol in patients who are immunocompromised.

|administration=* Topical |monitoring=There is limited information regarding Monitoring of Isopropyl alcohol in the drug label.

|IVCompat=There is limited information regarding IV Compatibility of Isopropyl alcohol in the drug label.

|drugBox=*

Template:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox entryTemplate:Chembox E numberTemplate:Chembox RTECSTemplate:Chembox UNNumberTemplate:Chembox AppearanceTemplate:Chembox DensityTemplate:Chembox MeltingPtTemplate:Chembox BoilingPtTemplate:Chembox SolubilityInWaterTemplate:Chembox SolubilityTemplate:Chembox pKaTemplate:Chembox RefractIndexTemplate:Chembox ViscosityTemplate:Chembox DipoleTemplate:Chembox Supplement
Template:Chembox header2 | Isopropyl alcohol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG
UNII
Properties
C3H8O
Molar mass 60.10 g·mol−1
Template:Chembox header2 | Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

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{{#subobject:

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{{#subobject:

 |Label Page=Isopropyl alcohol
 |Label Name=Isopropyl alcohol11.png

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  1. Reeve, W.; Erikson, C.M.; Aluotto, P.F. (1979). "A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides". Can. J. Chem. 57 (20): 2747. doi:10.1139/v79-444.
  2. 2.0 2.1 Yaws, C.L. (1999). Chemical Properties Handbook. McGraw-Hill. ISBN 0-07-073401-1.