Ischemic stroke differential diagnosis: Difference between revisions

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! rowspan="2" |Diseases
! rowspan="2" |Diseases
! colspan="5" |Diagnostic tests
! colspan="4" |Diagnostic tests
! colspan="4" |Physical Examination
! colspan="4" |Physical Examination
! colspan="4" |Symptoms
! colspan="4" |Symptoms
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! rowspan="2" |Other Findings
! rowspan="2" |Other Findings
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!CBC
!Na+, K+, Ca2+  
!Na+, K+, Ca2+  
!CT /MRI
!CT /MRI
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|style="background: #DCDCDC; padding: 5px; text-align: center;" | Brain tumour<ref name="pmid10582668">{{cite journal| author=Morgenstern LB, Frankowski RF| title=Brain tumor masquerading as stroke. | journal=J Neurooncol | year= 1999 | volume= 44 | issue= 1 | pages= 47-52 | pmid=10582668 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10582668  }} </ref>
|style="background: #DCDCDC; padding: 5px; text-align: center;" | Brain tumour<ref name="pmid10582668">{{cite journal| author=Morgenstern LB, Frankowski RF| title=Brain tumor masquerading as stroke. | journal=J Neurooncol | year= 1999 | volume= 44 | issue= 1 | pages= 47-52 | pmid=10582668 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10582668  }} </ref>
|style="background: #F5F5F5; padding: 5px;" |N
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Hemorrhagic stroke
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Hemorrhagic stroke
|style="background: #F5F5F5; padding: 5px;" |N
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|style="background: #DCDCDC; padding: 5px; text-align: center;" | Subdural hemorrhage
|style="background: #DCDCDC; padding: 5px; text-align: center;" | Subdural hemorrhage
|style="background: #F5F5F5; padding: 5px;" |N
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Neurosyphilis<ref name="pmid22482824">{{cite journal| author=Liu LL, Zheng WH, Tong ML, Liu GL, Zhang HL, Fu ZG et al.| title=Ischemic stroke as a primary symptom of neurosyphilis among HIV-negative emergency patients. | journal=J Neurol Sci | year= 2012 | volume= 317 | issue= 1-2 | pages= 35-9 | pmid=22482824 | doi=10.1016/j.jns.2012.03.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22482824  }} </ref><ref name="pmid24365430">{{cite journal |vauthors=Berger JR, Dean D |title=Neurosyphilis |journal=Handb Clin Neurol |volume=121 |issue= |pages=1461–72 |year=2014 |pmid=24365430 |doi=10.1016/B978-0-7020-4088-7.00098-5 |url=}}</ref>
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Neurosyphilis<ref name="pmid22482824">{{cite journal| author=Liu LL, Zheng WH, Tong ML, Liu GL, Zhang HL, Fu ZG et al.| title=Ischemic stroke as a primary symptom of neurosyphilis among HIV-negative emergency patients. | journal=J Neurol Sci | year= 2012 | volume= 317 | issue= 1-2 | pages= 35-9 | pmid=22482824 | doi=10.1016/j.jns.2012.03.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22482824  }} </ref><ref name="pmid24365430">{{cite journal |vauthors=Berger JR, Dean D |title=Neurosyphilis |journal=Handb Clin Neurol |volume=121 |issue= |pages=1461–72 |year=2014 |pmid=24365430 |doi=10.1016/B978-0-7020-4088-7.00098-5 |url=}}</ref>
| style="background: #F5F5F5; padding: 5px;" |lymphocytosis
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Complex or atypical migraine
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Complex or atypical migraine
|style="background: #F5F5F5; padding: 5px;" |N
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Conversion disorder  
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Conversion disorder  
|style="background: #F5F5F5; padding: 5px;" |N
|style="background: #F5F5F5; padding: 5px;" |↓
|style="background: #F5F5F5; padding: 5px;" |↓
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Electrolyte disturbance
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Electrolyte disturbance
|style="background: #F5F5F5; padding: 5px;" |N
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Intracranial neoplasm
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Intracranial neoplasm
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Meningitis or encephalitis
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Meningitis or encephalitis
|style="background: #F5F5F5; padding: 5px;" |TLC
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Multiple sclerosis exacerbation
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Multiple sclerosis exacerbation
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Seizure
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Seizure
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|style="background: #DCDCDC; padding: 5px; text-align: center;" |Hypoglycemia or hyperglycemia
|style="background: #DCDCDC; padding: 5px; text-align: center;" |Hypoglycemia or hyperglycemia
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Revision as of 02:21, 9 November 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Overview

Differential Diagnosis

Diseases Diagnostic tests Physical Examination Symptoms Past medical history Other Findings
Na+, K+, Ca2+ CT /MRI CSF Findings Gold standard test Motor Deficit Sensory deficit Speech or gait? Cranial

nerves

Headache LOC Motor weakness Abnormal sensations
Brain tumour[1] + MRI + + + + Cahexia
Hemorrhagic stroke + CT scan without contrast</ref></ref> + + + + + + Hypertension+
Subdural hemorrhage + CT scan without contrast[2][3] + + + + + + Trauma/fall
Neurosyphilis[4][5] + CSF VDRL-specifc

CSF FTA-Ab -sensitive[6]

+ + + + + STIs
Complex or atypical migraine Clinical assesment + + Family history of migraine
Conversion disorder Diagnosis of exclusion?? + + + + + +
Electrolyte disturbance
Intracranial neoplasm
Meningitis or encephalitis CSF analysis</ref> + + Fever, Neck

rigidity

Multiple sclerosis exacerbation + Clinical assesment and MRI </ref> + + + + History of relapses and remissions
Seizure Clinical assesment and EEG [7] + + + + History of similar episodes in the past
Hypoglycemia or hyperglycemia HbA1c + + + History of diabetes Palpitations, sweating

References

  1. Morgenstern LB, Frankowski RF (1999). "Brain tumor masquerading as stroke". J Neurooncol. 44 (1): 47–52. PMID 10582668.
  2. Liu LL, Zheng WH, Tong ML, Liu GL, Zhang HL, Fu ZG; et al. (2012). "Ischemic stroke as a primary symptom of neurosyphilis among HIV-negative emergency patients". J Neurol Sci. 317 (1–2): 35–9. doi:10.1016/j.jns.2012.03.003. PMID 22482824.
  3. Berger JR, Dean D (2014). "Neurosyphilis". Handb Clin Neurol. 121: 1461–72. doi:10.1016/B978-0-7020-4088-7.00098-5. PMID 24365430.
  4. Ho EL, Marra CM (2012). "Treponemal tests for neurosyphilis--less accurate than what we thought?". Sex Transm Dis. 39 (4): 298–9. doi:10.1097/OLQ.0b013e31824ee574. PMC 3746559. PMID 22421697.
  5. Manford M (2001). "Assessment and investigation of possible epileptic seizures". J Neurol Neurosurg Psychiatry. 70 Suppl 2: II3–8. PMC 1765557. PMID 11385043.

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