Iodoquinol

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Iodoquinol
YODOXIN® Package Insert
Description
Inactive Ingredients
Action
Indications
Contraindications
Warnings
Use in Pregnancy
Precautions
Adverse Reactions
Dosage and Administration
How Supplied
Storage

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The quinoline derivative diiodohydroxyquinoline (INN) or iodoquinol (USAN), can be used in the treatment of amoebiasis.[1] It is poorly absorbed from the gastrointestinal tract and is used as a luminal amebicide. It was discovered by Adco Co. and introduced as diiodohydroxyquinoline.[2] Susceptibility of Dientamoeba fragilis has been measured.[3]

Category

Amebicide

US Brand Names

ALA-SEPTIC®, ALCORTIN®, ALCORTIN A®, ALOQUIN®, DERMAZENE®, HYDROCORTISONE IODOQUINOL cream®, VYTONE cream®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings | Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | Directions For Use | How Supplied | Other Size Packages Available | Labels and Packages

Mechanisms of Action

References

  1. Ghaskadbi S, Vaidya VG (1989). "In vivo antimutagenic effect of ascorbic acid against mutagenicity of the common antiamebic drug diiodohydroxyquinoline". Mutat. Res. 222 (3): 219–22. doi:10.1016/0165-1218(89)90137-7. PMID 2493578. Unknown parameter |month= ignored (help)
  2. Page 1312. http://books.google.co.in/books?id=TIu28TH_iAYC&printsec=frontcover&source=gbs_ge_summary_r&cad=0#v=onepage&q&f=false
  3. Chan FT, Guan MX, Mackenzie AM, Diaz-Mitoma F (1994). "Susceptibility testing of Dientamoeba fragilis ATCC 30948 with iodoquinol, paromomycin, tetracycline, and metronidazole". Antimicrob. Agents Chemother. 38 (5): 1157–60. PMC 188168. PMID 8067755. Unknown parameter |month= ignored (help)