Interstitial lung disease: Difference between revisions

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==Classification==
==Classification==
Interstitial lung disease may be classified on the basis of lung response to tissue injury and include:
Interstitial lung disease may be classified on the basis of lung response to tissue injury and include:<ref>{{cite book | last = Kasper | first = Dennis | title = Harrison's principles of internal medicine | chapter =315: Interstitial Lung Diseases | editor1-last=Talmadge |editor1-first= E. King, Jr. | publisher = McGraw Hill Education | location = New York | year = 2015 | isbn = 0071802150 }}</ref>
*Lung response: Granulomatous
*Lung response: Granulomatous
*Lung response: Alveolitis, interstitial inflammation, and fibrosis
*Lung response: Alveolitis, interstitial inflammation, and fibrosis

Revision as of 22:11, 7 March 2018

Interstitial Lung Disease

Home

Patient Information

Overview

Classification

Fibrosis lung response
Occupational lung disease
Drug-induced lung injury
Radiation-induced lung injury
Smoking related interstitial lung disease
Idiopathic interstitial pneumonia
Pulmonary alveolar proteinosis
Lymphocytic infiltrative disorders
Pulmonary lymphangioleiomyomatosis
Pulmonary hemorrhage syndromes
Interstitial lung disease associated with systemic diseases
Granulomatous lung response

Pathophysiology

Differentiating Interstitial Lung Disease from other Diseases

Laboratory Finidngs

For the WikiPatient page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.

Synonyms and keywords: Diffuse parenchymal lung disease; DPLD; ILD

Overview

Classification

Interstitial lung disease may be classified on the basis of lung response to tissue injury and include:[1]

  • Lung response: Granulomatous
  • Lung response: Alveolitis, interstitial inflammation, and fibrosis

 
 
 
 
 
 
 
 
 
 
 
 
 
 
Interstitial lung disease
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Lung Response:
Granulomatous
 
 
 
 
 
 
 
 
 
 
 
Lung Response:
Alveolitis,
Interstitial Inflammation,
and Fibrosis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Known
 
 
 
 
 
Idiopathic (Unknown)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hypersensitivity pneumonitis (organic dusts)
 
Inorganic dusts
 
Sarcoidosis
 
Lymphomatoid granulomatosis
 
Granulomatous vasculitides
 
Bronchocentric granulomatosis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Beryllium
 
Silica
 
 
 
 
 
Eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome)
 
Granulomatosis with polyangiitis (Wegener)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Known cause
 
 
 
 
 
 
 
Idiopathic (Unknown)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Drug-induced pulmonary toxicity
 
Occupational and environmental exposure
 
Radiation-induced lung injury
 
Aspiration pneumonia
 
Smoking-related
 
Residual of acute respiratory distress syndrome
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Inhaled inorganic dust
 
Inhaled organic dusts
 
Inhaled agents other than inorganic or organic dusts
 
Desquamative interstitial pneumonia
 
Respiratory bronchiolitis–associated interstitial lung disease
 
Pulmonary Langerhans cell granulomatosis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pulmonary alveolar proteinosis
 
Idiopathic interstitial pneumonias
 
Lymphocytic infiltrative disorders
(lymphocytic interstitial pneumonitis
associated with connective tissue disease)
 
Connective tissue
diseases
 
Gastrointestinal or
liver diseases
 
Inherited diseases
 
Graft-versus-host disease
 
Pulmonary hemorrhage syndromes
 
Eosinophilic
pneumonias
 
Lymphangioleiomyomatosis
 
Amyloidosis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Major idiopathic interstitial pneumonias
 
Rare idiopathic interstitial pneumonias
 
Unclassifiable idiopathic interstitial pneumonias
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
• Idiopathic pulmonary fibrosis
• Idiopathic nonspecific interstitial pneumonia
• Respiratory bronchiolitis-interstitial lung disease
• Desquamative interstitial pneumonia
• Cryptogenic organising pneumonia
• Acute interstitial pneumonia
 
• Idiopathic lymphoid interstitial pneumonia
• Idiopathic pleuroparenchymal fibroelastosis
 
 
 
 
 
• Systemic lupus erythematosus
• Rheumatoid arthritis
• Ankylosing spondylitis
• Systemic sclerosis
• Sjögren syndrome
• Polymyositis
• Dermatomyositis
 
• Crohn disease
• Primary biliary cirrhosis
• Chronic active hepatitis
• Ulcerative colitis
 
• Tuberous sclerosis
• Neurofibromatosis
• Niemann-Pick disease
• Gaucher disease
• Hermansky-Pudlak syndrome
 
• Bone marrow transplantation
• Solid organ transplantation
 
• Goodpasture syndrome
• Idiopathic pulmonary hemosiderosis
• Isolated pulmonary capillaritis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Pathophysiology

References

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de:Interstitielle Lungenerkrankung fi:Keuhkoparenkyymisairaudet


Template:WikiDoc Sources

  1. Kasper, Dennis (2015). "315: Interstitial Lung Diseases". In Talmadge, E. King, Jr. Harrison's principles of internal medicine. New York: McGraw Hill Education. ISBN 0071802150.