Inorganic pyrophosphatase

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pyrophosphatase (inorganic) 1
Identifiers
SymbolPPA1
Alt. symbolsPP
Entrez5464
HUGO9226
OMIM179030
RefSeqNM_021129
UniProtQ15181
Other data
EC number3.6.1.1
LocusChr. 10 q11.1-q24
pyrophosphatase (inorganic) 2
Identifiers
SymbolPPA2
Entrez27068
HUGO28883
OMIM609988
RefSeqNM_176869
UniProtQ9H2U2
Other data
LocusChr. 4 q25

Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme that converts one molecule of pyrophosphate to two phosphate ions. This highly exergonic reaction (about -34KJ change in free energy) can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion, as in Lipid synthesis and other biochemical transformations.

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