Idiopathic pulmonary fibrosis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
==Laboratory findings== | ==Laboratory findings== | ||
Laboratory findings consistent with the diagnosis of idiopathic pulmonary fibrosis include: | |||
*Abnormal [[Arterial blood gas|ABG]] | |||
**May indicate [[hypoxia]], [[hypercapnia]], and [[respiratory acidosis]] | |||
*Abnormal [[sputum]] analysis | |||
**May contain [[bacteria]], such as [[mycobacterium tuberculosis]] or inorganic particles, such as asbestos bodies or organic particles | |||
*[[Peak flow meter|Peak flow]] assessment | |||
**May be below normal range which is 100 liters/minute for men, and 80 liters/minute for women | |||
*[[Spirometry]] | |||
**May indicate an [[Obstructive airway diseases|obstructive]] or [[Restrictive Lung Disease|restrictive]] pulmonary disease | |||
**A [[FEV1/FVC ratio]] < 80% indicates and [[Obstructive airway diseases|obstructive]] disease, such as asthma, whilst a [[FEV1/FVC ratio]] higher than [[Restrictive lung disease|restrictive]] pulmonary disease indicates a restrictive disease, such as [[pulmonary fibrosis]] | |||
*[[Complete blood count|CBC]] | |||
**May indicate [[anemia]], [[neutrophilia]], elevated [[Erythrocyte sedimentation rate|ESR]], elevated [[C-reactive protein|CRP]], and elevated [[Antibody|immunoglobulin]] | |||
*[[Bronchoscopy]] and [[bronchoalveolar lavage]] | |||
**May reveal mineral dust | |||
*[[Tuberculin skin test]] | |||
**To test for [[tuberculosis]], and induration > 5mm is positive | |||
*Stool examination for [[occult blood]] | |||
**May indicate [[Colorectal cancer|colorectal carcinoma]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 00:17, 15 March 2018
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Differentiating Idiopathic pulmonary fibrosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory findings
Laboratory findings consistent with the diagnosis of idiopathic pulmonary fibrosis include:
- Abnormal ABG
- May indicate hypoxia, hypercapnia, and respiratory acidosis
- Abnormal sputum analysis
- May contain bacteria, such as mycobacterium tuberculosis or inorganic particles, such as asbestos bodies or organic particles
- Peak flow assessment
- May be below normal range which is 100 liters/minute for men, and 80 liters/minute for women
- Spirometry
- May indicate an obstructive or restrictive pulmonary disease
- A FEV1/FVC ratio < 80% indicates and obstructive disease, such as asthma, whilst a FEV1/FVC ratio higher than restrictive pulmonary disease indicates a restrictive disease, such as pulmonary fibrosis
- CBC
- May indicate anemia, neutrophilia, elevated ESR, elevated CRP, and elevated immunoglobulin
- Bronchoscopy and bronchoalveolar lavage
- May reveal mineral dust
- Tuberculin skin test
- To test for tuberculosis, and induration > 5mm is positive
- Stool examination for occult blood
- May indicate colorectal carcinoma