Ichthyosis: Difference between revisions

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{{SI}}
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{{EH}}
'''For patient information on this page, click [[Icthyosis (patient information)|here]]'''
 
{{CMG}} {{AE}} {{RT}} {{KS}}
 
{{SK}} Scaling skin, Fish scale disease


==Overview==
==Overview==
'''Ichthyosis''' is a family of [[genetic disorder|genetic]] [[dermatology|dermatological]] conditions seen in humans and domestic animals. The word comes from [[Greek language|Greek]] ''ιχθύωσις'' lit. "forming fish", as people or animals with ichthyosis have scaly skin which can vaguely resemble the [[scale (zoology)|scale]]s of a fish.  
'''Ichthyosis''' is a family of [[genetic disorder|genetic]] [[dermatology|dermatological]] conditions seen in humans and domestic animals. People or animals with ichthyosis have scaly skin which can vaguely resemble the [[scale (zoology)|scale]]s of a fish.


The term ichthyosis is sometimes used to refer to the specific condition [[ichthyosis vulgaris]]. Ichthyosis was formerly referred to as "pseudo-leprosy," as it can produce an appearance superficially similar to that of [[leprosy]].
==Historical Perspective==
The word comes from [[Greek language|Greek]] ''ιχθύωσις'' lit. "forming fish", as people or animals with ichthyosis have scaly skin which can vaguely resemble the [[scale (zoology)|scale]]s of a fish.  


==Types==
The term ichthyosis is sometimes used to refer to the specific condition [[ichthyosis vulgaris]].  Ichthyosis was formerly referred to as "pseudo-leprosy," as it can produce an appearance superficially similar to that of [[leprosy]].
 
==Classification==
While [[ichthyosis acquisita]] is [[Acquired disorder|acquired]] (as its name indicates), most forms of ichthyosis are considered [[congenital]]. These types include:
While [[ichthyosis acquisita]] is [[Acquired disorder|acquired]] (as its name indicates), most forms of ichthyosis are considered [[congenital]]. These types include:


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* [[Netherton's syndrome]]
* [[Netherton's syndrome]]
* [[Sjögren-Larsson syndrome]]
* [[Sjögren-Larsson syndrome]]
==Epidemiology and Demographics==
Ethnicity is not associated with ichthyosis.


==Ichthyosis in domestic dogs==
==Ichthyosis in domestic dogs==
Ichthyosis of varying severity is well-documented in some popular [[dog breed|breeds]] of domestic [[dog]]s. The most common breeds in which this condition manifests itself are [[Golden retriever]]s, [[American bulldog]]s, [[Jack Russell terrier]]s, and [[Cairn terrier]]s.
Ichthyosis of varying severity is well-documented in some popular [[dog breed|breeds]] of domestic [[dog]]s. The most common breeds in which this condition manifests itself are [[Golden retriever]]s, [[American bulldog]]s, [[Jack Russell terrier]]s, and [[Cairn terrier]]s.


==Diagnosis==
==Diagnosis==
A physician (or veterinarian) often can diagnose ichthyosis by looking at the skin. A family history is also very useful. In some cases, a skin biopsy will be done to help to confirm the diagnosis. In a biopsy, a small piece of skin is removed and examined under a microscope. In rare instances, genetic testing may be helpful in making a diagnosis.  
===Symptoms===
Ichthyosis is not more or less common in any ethnic group. As of now, there is no way to prevent ichthyosis.
* Dry skin
* Scaly skin
* Thick skin
 
===Physical Examination===
* Dry, scaly skin
=====Extremity=====
<gallery>
Image:Ichthyosis vulgaris01.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
Image:Ichthyosis vulgaris02.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Ichthyosis vulgaris03.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
 
Image:Ichthyosis vulgaris08.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
 
 
Image:Ichthyosis vulgaris09.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
Image:Ichthyosis vulgaris10.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
 
 
</gallery>
 
=====Trunk=====
<gallery>
 
 
 
Image:Ichthyosis vulgaris04.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
Image:Ichthyosis vulgaris05.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
 
 
 
 
Image:Ichthyosis vulgaris06.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
 
 
Image:Ichthyosis vulgaris07.jpg|Icthyosis vulgaris. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
 
 
 
</gallery>
 
===Lab tests===
* Skin biopsy


==Treatments==
==Treatments==
Treatments for ichthyosis often take the form of topical application of creams and [[emollient]] oils, in an attempt to hydrate the skin. [[Retinoid]]s are also used for some conditions. Exposure to sunlight may improve or worsen the condition.
Treatments for ichthyosis often take the form of topical application of creams and [[emollient]] oils, in an attempt to hydrate the skin. [[Retinoid]]s are also used for some conditions. Exposure to sunlight may improve or worsen the condition.
 
There can be ocular manifestations of ichthyosis, such as corneal and ocular surface diseases.  Vascularizing keratitis, which is more commonly found in congenital [[keratitis-ichythosis-deafness]] (KID), may worsen with isotretinoin therapy.  Ectropion, if it occurs, can be treated surgically after skin hydration.
 
As of now, there is no way to prevent ichthyosis.
 
==References==


There can be ocular manifestations of ichthyosis, such as corneal and ocular surface diseases.  Vascularizing keratitis, which is more commonly found in congenital keratitis-ichythosis-deafness (KID), may worsen with isotretinoin therapy.  Ectropion, if it occurs, can be treated surgically after skin hydration.
{{reflist|2}}


==See also==
==See also==
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==External links==
==External links==
* [http://www.bidmc.org/YourHealth/ConditionsAZ.aspx?ChunkID=11753 Beth Israel Deaconess Medical Center: Ichthyosis]
* [http://www.scalyskin.org/ Foundation for Ichthyosis and Related Skin Types]
* [http://www.scalyskin.org/ Foundation for Ichthyosis and Related Skin Types]
* [http://www.ichthyosis.com/ Ichthyosis Information]
* [http://www.ichthyosis.com/ Ichthyosis Information]
* [http://www.time.com/time/magazine/article/0,9171,816892,00.html Ichthyosis and Hypnosis]
* {{DermAtlas|1896838546}}


{{Congenital malformations and deformations of integument}}
{{Congenital malformations and deformations of integument}}
{{SIB}}


[[de:Ichthyose]]
[[de:Ichthyose]]
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Latest revision as of 14:54, 7 September 2014

Ichthyosis
ICD-10 Q80
ICD-9 757.1
DiseasesDB 6646
MeSH D007057

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Kiran Singh, M.D. [3]

Synonyms and keywords: Scaling skin, Fish scale disease

Overview

Ichthyosis is a family of genetic dermatological conditions seen in humans and domestic animals. People or animals with ichthyosis have scaly skin which can vaguely resemble the scales of a fish.

Historical Perspective

The word comes from Greek ιχθύωσις lit. "forming fish", as people or animals with ichthyosis have scaly skin which can vaguely resemble the scales of a fish.

The term ichthyosis is sometimes used to refer to the specific condition ichthyosis vulgaris. Ichthyosis was formerly referred to as "pseudo-leprosy," as it can produce an appearance superficially similar to that of leprosy.

Classification

While ichthyosis acquisita is acquired (as its name indicates), most forms of ichthyosis are considered congenital. These types include:

Some types of ichthyosis include:

Epidemiology and Demographics

Ethnicity is not associated with ichthyosis.

Ichthyosis in domestic dogs

Ichthyosis of varying severity is well-documented in some popular breeds of domestic dogs. The most common breeds in which this condition manifests itself are Golden retrievers, American bulldogs, Jack Russell terriers, and Cairn terriers.

Diagnosis

Symptoms

  • Dry skin
  • Scaly skin
  • Thick skin

Physical Examination

  • Dry, scaly skin
Extremity
Trunk

Lab tests

  • Skin biopsy

Treatments

Treatments for ichthyosis often take the form of topical application of creams and emollient oils, in an attempt to hydrate the skin. Retinoids are also used for some conditions. Exposure to sunlight may improve or worsen the condition.

There can be ocular manifestations of ichthyosis, such as corneal and ocular surface diseases. Vascularizing keratitis, which is more commonly found in congenital keratitis-ichythosis-deafness (KID), may worsen with isotretinoin therapy. Ectropion, if it occurs, can be treated surgically after skin hydration.

As of now, there is no way to prevent ichthyosis.

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 "Dermatology Atlas".

See also

External links

Template:Congenital malformations and deformations of integument

de:Ichthyose it:Ittiosi no:Iktyose


Template:WikiDoc Sources