ITGB7

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Integrin, beta 7
PDB rendering based on 2brq.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols ITGB7 ;
External IDs Template:OMIM5 Template:MGI HomoloGene20247
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Integrin, beta 7, also known as ITGB7, is a human gene.[1]


References

  1. "Entrez Gene: ITGB7 integrin, beta 7".

Further reading

  • Rüegg C, Postigo AA, Sikorski EE; et al. (1992). "Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering". J. Cell Biol. 117 (1): 179–89. PMID 1372909.
  • Chan BM, Elices MJ, Murphy E, Hemler ME (1992). "Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY". J. Biol. Chem. 267 (12): 8366–70. PMID 1373725.
  • Jiang WM, Jenkins D, Yuan Q; et al. (1992). "The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1". Int. Immunol. 4 (9): 1031–40. PMID 1382574.
  • Baker E, Sutherland GR, Jiang WM; et al. (1992). "Mapping of the human integrin beta 7 gene (ITG beta 7) to 12q13.13 by non-isotopic in situ hybridization". Mamm. Genome. 2 (4): 272–3. PMID 1543919.
  • Yuan QA, Jiang WM, Krissansen GW, Watson JD (1992). "Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains". Int. Immunol. 3 (12): 1373–4. PMID 1777426.
  • Erle DJ, Rüegg C, Sheppard D, Pytela R (1991). "Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes". J. Biol. Chem. 266 (17): 11009–16. PMID 2040616.
  • Yuan QA, Jiang WM, Krissansen GW, Watson JD (1991). "Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains". Int. Immunol. 2 (11): 1097–108. PMID 2083230.
  • Erle DJ, Brown T, Christian D, Aris R (1994). "Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression". Am. J. Respir. Cell Mol. Biol. 10 (3): 237–44. PMID 7509610.
  • Postigo AA, Sánchez-Mateos P, Lazarovits AI; et al. (1993). "Alpha 4 beta 7 integrin mediates B cell binding to fibronectin and vascular cell adhesion molecule-1. Expression and function of alpha 4 integrins on human B lymphocytes". J. Immunol. 151 (5): 2471–83. PMID 7689608.
  • Shaw SK, Cepek KL, Murphy EA; et al. (1994). "Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution". J. Biol. Chem. 269 (8): 6016–25. PMID 8119947.
  • Tidswell M, Pachynski R, Wu SW; et al. (1997). "Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1". J. Immunol. 159 (3): 1497–505. PMID 9233649.
  • Tan K, Casasnovas JM, Liu JH; et al. (1998). "The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition". Structure. 6 (6): 793–801. PMID 9655832.
  • Rietzler M, Bittner M, Kolanus W; et al. (1998). "The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins". J. Biol. Chem. 273 (42): 27459–66. PMID 9765275.
  • Taraszka KS, Higgins JM, Tan K; et al. (2000). "Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin". J. Exp. Med. 191 (9): 1555–67. PMID 10790430.
  • Higgins JM, Cernadas M, Tan K; et al. (2000). "The role of alpha and beta chains in ligand recognition by beta 7 integrins". J. Biol. Chem. 275 (33): 25652–64. doi:10.1074/jbc.M001228200. PMID 10837471.
  • Puig-Kröger A, Sanz-Rodríguez F, Longo N; et al. (2000). "Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells". J. Immunol. 165 (8): 4338–45. PMID 11035069.
  • Guilliano MJ, Foxx-Orenstein AE, Lebman DA (2001). "The microenvironment of human Peyer's patches inhibits the increase in CD38 expression associated with the germinal center reaction". J. Immunol. 166 (4): 2179–85. PMID 11160270.
  • Calderwood DA, Huttenlocher A, Kiosses WB; et al. (2002). "Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration". Nat. Cell Biol. 3 (12): 1060–8. doi:10.1038/ncb1201-1060. PMID 11781567.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Calderwood DA, Fujioka Y, de Pereda JM; et al. (2003). "Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2272–7. doi:10.1073/pnas.262791999. PMID 12606711.

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