IHPK2

Revision as of 23:43, 31 August 2017 by en>KolbertBot (Bot: HTTP→HTTPS)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Inositol hexakisphosphate kinase 2 is an enzyme that in humans is encoded by the IP6K2 gene.[1][2]

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.[2]

References

  1. Saiardi A, Erdjument-Bromage H, Snowman AM, Tempst P, Snyder SH (May 2000). "Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases". Curr Biol. 9 (22): 1323–6. doi:10.1016/S0960-9822(00)80055-X. PMID 10574768.
  2. 2.0 2.1 "Entrez Gene: IHPK2 inositol hexaphosphate kinase 2".

Further reading

See also