IFNA2

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Interferon, alpha 2
PDB rendering based on 1itf.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols IFNA2 ; IFNA; INFA2; MGC125764; MGC125765
External IDs Template:OMIM5 HomoloGene86655
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Interferon, alpha 2, also known as IFNA2, is a human gene.[1]


References

  1. "Entrez Gene: IFNA2 interferon, alpha 2".

Further reading

  • Conti L, Fantuzzi L, Del Cornò M; et al. (2005). "Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis". Immunobiology. 209 (1–2): 99–115. PMID 15481145.
  • Capobianchi MR, Ankel H, Ameglio F; et al. (1992). "Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer". AIDS Res. Hum. Retroviruses. 8 (5): 575–9. PMID 1381203.
  • Olopade OI, Bohlander SK, Pomykala H; et al. (1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. PMID 1385305.
  • Flores I, Mariano TM, Pestka S (1991). "Human interferon omega (omega) binds to the alpha/beta receptor". J. Biol. Chem. 266 (30): 19875–7. PMID 1834641.
  • Tyring SK, Cauda R, Tumbarello M; et al. (1991). "Synthetic peptides corresponding to sequences in HIV envelope gp41 and gp120 enhance in vitro production of interleukin-1 and tumor necrosis factor but depress production of interferon-alpha, interferon-gamma and interleukin-2". Viral Immunol. 4 (1): 33–42. PMID 1905933.
  • Adolf GR, Kalsner I, Ahorn H; et al. (1991). "Natural human interferon-alpha 2 is O-glycosylated". Biochem. J. 276 ( Pt 2): 511–8. PMID 2049076.
  • Stine KC, Bolognesi D, Weinhold KJ (1989). "Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity". Journal of biological response modifiers. 8 (5): 501–10. PMID 2552026.
  • Oliver G, Balbás P, Valle F; et al. (1986). "[Cloning of human leukocyte interferon cDNA and a strategy for its production in E. coli]". Rev. Latinoam. Microbiol. 27 (2): 141–50. PMID 3906813.
  • Streuli M, Nagata S, Weissmann C (1980). "At least three human type alpha interferons: structure of alpha 2". Science. 209 (4463): 1343–7. PMID 6158094.
  • Allen G, Fantes KH (1981). "A family of structural genes for human lymphoblastoid (leukocyte-type) interferon". Nature. 287 (5781): 408–11. PMID 6159537.
  • Goeddel DV, Yelverton E, Ullrich A; et al. (1981). "Human leukocyte interferon produced by E. coli is biologically active". Nature. 287 (5781): 411–6. PMID 6159538.
  • Wetzel R (1981). "Assignment of the disulphide bonds of leukocyte interferon". Nature. 289 (5798): 606–7. PMID 6162107.
  • Goeddel DV, Leung DW, Dull TJ; et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs". Nature. 290 (5801): 20–6. PMID 6163083.
  • Maeda S, McCandliss R, Gross M; et al. (1981). "Construction and identification of bacterial plasmids containing nucleotide sequence for human leukocyte interferon". Proc. Natl. Acad. Sci. U.S.A. 77 (12): 7010–3. PMID 6164056.
  • Lawn RM, Gross M, Houck CM; et al. (1982). "DNA sequence of a major human leukocyte interferon gene". Proc. Natl. Acad. Sci. U.S.A. 78 (9): 5435–9. PMID 6170983.
  • Weber H, Weissmann C (1983). "Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli". Nucleic Acids Res. 11 (16): 5661–9. PMID 6310510.
  • Ameglio F, Capobianchi MR, Castilletti C; et al. (1994). "Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines". Clin. Exp. Immunol. 95 (3): 455–8. PMID 7511078.
  • Ankel H, Capobianchi MR, Castilletti C, Dianzani F (1994). "Interferon induction by HIV glycoprotein 120: role of the V3 loop". Virology. 205 (1): 34–43. doi:10.1006/viro.1994.1617. PMID 7526537.
  • Nair MP, Chadha KC, Stadler I; et al. (1995). "Differential effects of human immunodeficiency virus type 1 envelope protein gp120 on interferon production by mononuclear cells from adults and neonates". Clin. Diagn. Lab. Immunol. 2 (4): 434–8. PMID 7583919.
  • Lee N, Ni D, Brissette R; et al. (1995). "Interferon-alpha 2 variants in the human genome". J. Interferon Cytokine Res. 15 (4): 341–9. PMID 7627809.

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