Hypophysitis

Jump to navigation Jump to search
Hypophysitis

WikiDoc Resources for Hypophysitis

Articles

Most recent articles on Hypophysitis

Most cited articles on Hypophysitis

Review articles on Hypophysitis

Articles on Hypophysitis in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Hypophysitis

Images of Hypophysitis

Photos of Hypophysitis

Podcasts & MP3s on Hypophysitis

Videos on Hypophysitis

Evidence Based Medicine

Cochrane Collaboration on Hypophysitis

Bandolier on Hypophysitis

TRIP on Hypophysitis

Clinical Trials

Ongoing Trials on Hypophysitis at Clinical Trials.gov

Trial results on Hypophysitis

Clinical Trials on Hypophysitis at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Hypophysitis

NICE Guidance on Hypophysitis

NHS PRODIGY Guidance

FDA on Hypophysitis

CDC on Hypophysitis

Books

Books on Hypophysitis

News

Hypophysitis in the news

Be alerted to news on Hypophysitis

News trends on Hypophysitis

Commentary

Blogs on Hypophysitis

Definitions

Definitions of Hypophysitis

Patient Resources / Community

Patient resources on Hypophysitis

Discussion groups on Hypophysitis

Patient Handouts on Hypophysitis

Directions to Hospitals Treating Hypophysitis

Risk calculators and risk factors for Hypophysitis

Healthcare Provider Resources

Symptoms of Hypophysitis

Causes & Risk Factors for Hypophysitis

Diagnostic studies for Hypophysitis

Treatment of Hypophysitis

Continuing Medical Education (CME)

CME Programs on Hypophysitis

International

Hypophysitis en Espanol

Hypophysitis en Francais

Business

Hypophysitis in the Marketplace

Patents on Hypophysitis

Experimental / Informatics

List of terms related to Hypophysitis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords:Autoimmune hypophysitis, lymphocytic hypophysitis

Overview

Hypophysitis is the inflammation of the pituitary gland that typically results in some degree of pituitary dysfunction, ranging from under secretion of some pituitary hormones to complete panhypopituitarism requiring lifelong hormone supplementation. While hypophysitis by itself is seldom life-threatening, the sequelae of pituitary inflammation, particularly adrenal insufficiency and severe hypothyroidism, may be fatal if unrecognized and left untreated. There are several recognized causes of hypophysitis, including lymphocytic infiltration, granulomatous infiltration (e.g. in the setting of a systemic granulomatous disease such as sarcoidosis or granulomatosis with polyangiitis), and cell-mediated autoimmune reactivity in the setting of treatment of certain solid tumors with immunomodulatory checkpoint inhibitors (i.e. CTLA-4 inhibitors and PD-1 inhibitors). Although there are several different subtypes of hypophysitis, there are many commonalities in the diagnostic evaluation and treatment of this rare endocrinopathy.

Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs



Template:WikiDoc Sources