Hepatocellular adenoma causes: Difference between revisions

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==Overview==
==Overview==
The [[Causality|causes]] of [[hepatocellular adenoma]] include [[Oral contraceptive|oral contraceptive medications]], [[pregnancy]], long term use of [[anabolic]] [[Androgen|androgenic]] [[Steroid|steroids]], [[maturity onset diabetes of the young]], [[metabolic syndrome]], [[obesity]], [[Glycogen storage disease|glycogen storage diseases]], [[clomiphene]] and [[vascular disorders]] like [[portal vein]] [[agenesis]], [[Budd-Chiari syndrome|budd chiari syndrome]] and [[hereditary hemorrhagic telangiectasia]].
The [[Causality|causes]] of hepatocellular adenoma can include [[Oral contraceptive|oral contraceptive medications]], [[pregnancy]], long term use of [[anabolic]] [[Androgen|androgenic]] [[Steroid|steroids]], [[maturity onset diabetes of the young]], [[metabolic syndrome]], [[obesity]], [[Glycogen storage disease|glycogen storage diseases]], [[clomiphene]], and [[vascular disorders]] like [[portal vein]] [[agenesis]], [[Budd-Chiari syndrome|budd chiari syndrome]], and [[hereditary hemorrhagic telangiectasia]].


==Causes==
==Causes==
* The [[Causality|causes]] of [[hepatocellular adenoma]] include;<ref>{{Cite journal
The [[Causality|causes]] of hepatocellular adenoma can include;<ref>{{Cite journal
  | author = [[M. Kawakatsu]], [[V. Vilgrain]], [[S. Erlinger]] & [[H. Nahum]]
  | author = [[M. Kawakatsu]], [[V. Vilgrain]], [[S. Erlinger]] & [[H. Nahum]]
  | title = Disappearance of liver cell adenoma: CT and MR imaging
  | title = Disappearance of liver cell adenoma: CT and MR imaging
Line 110: Line 110:
  | pmid = 4126557
  | pmid = 4126557
}}</ref>
}}</ref>
** [[Oral contraceptive|Oral contraceptive medications]]
 
*** The [[Causality|causal]] relationship is proportional to the [[Hormone|hormonal]] [[dose]] and duration of [[medication]], highest in women over 30 years of [[age]] and after 24 months of using [[Oral contraceptive|oral contraceptives]].
*[[Oral contraceptive|Oral contraceptive medications]]
** [[Pregnancy]]
*[[Pregnancy]]
*** It appears to stimulate rapid [[growth]] in these [[Lesion|lesions]] with the risk of potentially [[fatal]] spontaneous [[rupture]].
*[[Glycogen storage disease type I|Glycogen storage disease types I]],[[Glycogen storage disease type II|II]] and [[Glycogen storage disease type IV|IV]]
** [[Glycogen storage disease type I|Glycogen storage disease types I]],[[Glycogen storage disease type II|II]] and [[Glycogen storage disease type IV|IV]]
*Long term use of [[anabolic]] [[Androgen|androgenic]] [[Steroid|steroids]]
** Long term use of [[anabolic]] [[Androgen|androgenic]] [[Steroid|steroids]]
*[[Metabolic syndrome]]
** [[Metabolic syndrome]]
*[[Maturity onset diabetes of the young|Maturity onset diabetes of young (MODY)]]
** [[Maturity onset diabetes of the young|Maturity onset diabetes of young (MODY)]]
*[[Obesity]]
** [[Obesity]]
*[[Clomiphene]]
** [[Clomiphene]]
*[[Familial adenomatous polyposis]]
** [[Familial adenomatous polyposis]]
*[[Vascular disorders]]
** [[Vascular disorders]] such as [[portal vein]] [[agenesis]], [[Budd-Chiari syndrome]] and [[hereditary hemorrhagic telangiectasia]].
**[[Portal vein]] [[agenesis]]
**[[Budd-Chiari syndrome]]  
**[[Hereditary hemorrhagic telangiectasia]]


==References==
==References==

Revision as of 22:21, 19 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]

Overview

The causes of hepatocellular adenoma can include oral contraceptive medications, pregnancy, long term use of anabolic androgenic steroids, maturity onset diabetes of the young, metabolic syndrome, obesity, glycogen storage diseases, clomiphene, and vascular disorders like portal vein agenesis, budd chiari syndrome, and hereditary hemorrhagic telangiectasia.

Causes

The causes of hepatocellular adenoma can include;[1][2][3][4][5][6][7][8][9]

References

  1. M. Kawakatsu, V. Vilgrain, S. Erlinger & H. Nahum (1997). "Disappearance of liver cell adenoma: CT and MR imaging". Abdominal imaging. 22 (3): 274–276. PMID 9107649. Unknown parameter |month= ignored (help)
  2. W. H. Marks, N. Thompson & H. Appleman (1988). "Failure of hepatic adenomas (HCA) to regress after discontinuance of oral contraceptives. An association with focal nodular hyperplasia (FNH) and uterine leiomyoma". Annals of surgery. 208 (2): 190–195. PMID 2840865. Unknown parameter |month= ignored (help)</ref<ref>H. Tesluk & J. Lawrie (1981). "Hepatocellular adenoma. Its transformation to carcinoma in a user of oral contraceptives". Archives of pathology & laboratory medicine. 105 (6): 296–299. PMID 6263214. Unknown parameter |month= ignored (help)
  3. D. Carrasco, M. Barrachina, M. Prieto & J. Berenguer (1984). "Clomiphene citrate and liver-cell adenoma". The New England journal of medicine. 310 (17): 1120–1121. doi:10.1056/NEJM198404263101716. PMID 6323982. Unknown parameter |month= ignored (help)
  4. G. B. Coombes, J. Reiser, F. J. Paradinas & I. Burn (1978). "An androgen-associated hepatic adenoma in a trans-sexual". The British journal of surgery. 65 (12): 869–870. PMID 737424. Unknown parameter |month= ignored (help)
  5. U. Beuers, W. O. Richter, M. M. Ritter, B. Wiebecke & P. Schwandt (1991). "Klinefelter's syndrome and liver adenoma". Journal of clinical gastroenterology. 13 (2): 214–216. PMID 1851773. Unknown parameter |month= ignored (help)
  6. N. S. Alshak, J. Cocjin, L. Podesta, R. van de Velde, L. Makowka, P. Rosenthal & S. A. Geller (1994). "Hepatocellular adenoma in glycogen storage disease type IV". Archives of pathology & laboratory medicine. 118 (1): 88–91. PMID 8285839. Unknown parameter |month= ignored (help)
  7. P. Labrune, P. Trioche, I. Duvaltier, P. Chevalier & M. Odievre (1997). "Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature". Journal of pediatric gastroenterology and nutrition. 24 (3): 276–279. PMID 9138172. Unknown parameter |month= ignored (help)
  8. S. Bala, P. H. Wunsch & W. G. Ballhausen (1997). "Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53". Gastroenterology. 112 (3): 919–922. PMID 9041254. Unknown parameter |month= ignored (help)
  9. J. K. Baum, J. J. Bookstein, F. Holtz & E. W. Klein (1973). "Possible association between benign hepatomas and oral contraceptives". Lancet (London, England). 2 (7835): 926–929. PMID 4126557. Unknown parameter |month= ignored (help)


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