Hepatitis E causes: Difference between revisions

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==Taxonomy==
==Taxonomy==
Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Hepeviridae; Hepevirus
[[Virus]]es; ssRNA viruses; ssRNA positive-strand viruses; [[Hepeviridae]]; [[Hepevirus]]<ref name=NCBI>{{cite web | title = Hepatitis E virus taxonomy | url = http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=12461 }}</ref>


==Biology==
==Biology==

Revision as of 01:08, 19 August 2014

Hepatitis E virus
TEM micrograph of hepatitis E virions.
TEM micrograph of hepatitis E virions.
Virus classification
Group: Group IV ((+)ssRNA)
Family: Hepeviridae
Genus: Hepevirus
Species: Hepatitis E virus

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2] Jolanta Marszalek, M.D. [3]

Overview

Taxonomy

Viruses; ssRNA viruses; ssRNA positive-strand viruses; Hepeviridae; Hepevirus[1]

Biology

The viral particles are 27 to 34 nanometers in diameter, are non-enveloped and contain a single-strand of positive-sense RNA that is approximately 7300 bases in length. The virus particle was first visualised in 1983[2] but was only molecularly cloned in 1990.[3]

It was previously classified family Caliciviridae. However, its genome more closely resembles the rubella virus. It is now classified in a new virus family, named as Hepeviridae.

  • Caused by the Hepatitis E virus (HEV)
  • HEV is found in the stool (feces) of persons and animals with hepatitis E.
  • HEV is spread by eating or drinking contaminated food or water.
  • Transmission from person to person occurs less commonly than with hepatitis A virus
  • Most outbreaks in developing countries have been associated with contaminated drinking water. [4]

References

  1. "Hepatitis E virus taxonomy".
  2. Balayan MS, Andjaparidze AG, Savinskaya SS; et al. (1983). "Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route". Intervirology. 20 (1): 23–31. PMID 6409836.
  3. Reyes GR, Purdy MA, Kim JP; et al. (1990). "Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis". Science. 247 (4948): 1335–9. doi:10.1126/science.2107574. PMID 2107574.