Hepatitis D screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]

Screening

Drug treatment programs should screen all patients for immunity to hepatitis B. Routine screening for hepatitis D is not indicated in persons who are HBsAg positive but asymptomatic. However, the following screening and prevention procedures may be appropriate:[1]

  • Patients known to be HBsAg positive who have acute or chronic hepatitis may be tested for hepatitis D. The followup care and counseling, however, of a person co-infected with hepatitis D is not different from that of a person who is HBsAg positive. Therefore, knowing if the patient is co-infected with hepatitis D is of limited clinical significance.
  • Patients with acute hepatitis B who are not yet HBsAg positive, but are immunoglobulin M (IgM) hepatitis B core antibody (anti-HBc) positive, may be tested for HDV; however, again, the presence of HDV antibody will not alter the care or counseling of such a patient.
  • Patients who are HBsAg positive and/or HDV antibody positive should be advised not to share razors, toilet articles, or drinking and eating utensils.
  • Patients who are not already immune to hepatitis B virus should be vaccinated against the virus.
  • Screening is not necessary in the general population at no risk for HBV or HDV.

References

  1. Center for Substance Abuse Treatment. Screening for Infectious Diseases Among Substance Abusers. Rockville (MD): Substance Abuse and Mental Health Services Administration (US); 1993. (Treatment Improvement Protocol (TIP) Series, No. 6.) Chapter 15 - Viral Hepatitis D.

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