Hepatitis C risk factors: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
{{#widget:SchemaSnippet}}
{{#widget:SchemaSnippet}}
* Intravenous drug users (IVDU)
* Blood transfusion before 1990
*:* Current transfusion-associated risk:  < 1/100,000
*:* Comparative risks:  [[Hepatitis B]] Virus (HBV) 1/63,000, [[HIV]] 1/493,000
*:* Residual risk due to recently infected donors (10 week window)
* Percutaneous exposures
*:* Needle stick transmission:  ~3% HCV, 30% HBV, 0.3% HIV
* Lesser Risk Factors
*:* High-risk sexual behavior
*:* Low socioeconomic status (unclear mechanisms)
*:*:* Sexual transmission inefficient
*:*:* [[HIV]] coinfection increases sexual and maternal-fetal transmission
* Risk Factors For Progression
*:* Alcohol use
*:* HIV or HBV coinfection
*:* Older age at infection, male sex


*Number of new infections per year has declined from an average of 240,000 in the 1980s to about 26,000 in 2004.
{{CMG}}
*Most infections are due to illegal injection drug use.
==Overview==
*Transfusion-associated cases occurred prior to blood donor screening; now occurs in less than one per 2 million transfused units of blood.  
The most important mode of HCV transmission is percutaneous blood exposure. Intravenous drug use is currently considered the most important risk factor for HCV infection. Populations at highest risk of HCV infection are those who have received blood and blood products, especially before 1992, and those who have received unsafe therapeutic injections.
*Estimated 4.1 million (1.6%) Americans have been infected with HCV, of whom 3.2 million are chronically infected.  
*The risk for perinatal HCV transmission is about 4%
*If coinfected with HIV the risk for perinatal infection is about 19%


==Risk Factors==
Percutaneous exposure to blood is the most important mode of HCV transmission.
The following are the most important risk factors for HCV infection<ref name="pmid17552026">{{cite journal| author=Alter MJ| title=Epidemiology of hepatitis C virus infection. | journal=World J Gastroenterol | year= 2007 | volume= 13 | issue= 17 | pages= 2436-41 | pmid=17552026 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17552026  }} </ref>:
*'''[[Injecting drug use]]''' is nowadays the most important risk factor
*'''[[Transfusion]] of blood and blood products''', especially before 1992
*'''Unsafe therapeutic [[injections]]''', especially in Hemophilia patients before 1987
Other less important risk factors are<ref name="pmid17552026">{{cite journal| author=Alter MJ| title=Epidemiology of hepatitis C virus infection. | journal=World J Gastroenterol | year= 2007 | volume= 13 | issue= 17 | pages= 2436-41 | pmid=17552026 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17552026  }} </ref>:
*[[Hemodialysis]]
*Solid organ [[transplantation]] from infected donors
*Occupational exposure to blood, such as contaminated needle sticks
*Birth to infected mother in cases of detectable maternal [[HCV PCR]] at [[delivery]]
*Sexual intercourse with infected partner
*Sexual intercourse with multiple partners
*[[HIV]] infection
*[[Tattoo]] or [[piercing]] with infected needle sticks
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 03:04, 28 July 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The most important mode of HCV transmission is percutaneous blood exposure. Intravenous drug use is currently considered the most important risk factor for HCV infection. Populations at highest risk of HCV infection are those who have received blood and blood products, especially before 1992, and those who have received unsafe therapeutic injections.


Risk Factors

Percutaneous exposure to blood is the most important mode of HCV transmission. The following are the most important risk factors for HCV infection[1]:

  • Injecting drug use is nowadays the most important risk factor
  • Transfusion of blood and blood products, especially before 1992
  • Unsafe therapeutic injections, especially in Hemophilia patients before 1987

Other less important risk factors are[1]:

  • Occupational exposure to blood, such as contaminated needle sticks
  • Birth to infected mother in cases of detectable maternal HCV PCR at delivery
  • Sexual intercourse with infected partner
  • Sexual intercourse with multiple partners
  • HIV infection
  • Tattoo or piercing with infected needle sticks

References

  1. 1.0 1.1 Alter MJ (2007). "Epidemiology of hepatitis C virus infection". World J Gastroenterol. 13 (17): 2436–41. PMID 17552026.

Template:WH Template:WS

Cookies help us deliver our services. By using our services, you agree to our use of cookies.

Navigation menu