Hepatitis C natural history: Difference between revisions
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*5–20 people will go on to develop cirrhosis over a period of 20–30 years | *5–20 people will go on to develop cirrhosis over a period of 20–30 years | ||
*1–5 people will die from cirrhosis or liver cancer | *1–5 people will die from cirrhosis or liver cancer | ||
==Complications== | |||
*Hepatitis C infection can continue over many years leading to chronic hepatitis | |||
*Over years, liver may undergo extensive damage and scarring resulting in [[cirrhosis]] | |||
*[[Liver failure]] | |||
*Hepatocellular carcinoma may occur in patients with chronic hepatitis C infection.<ref name="pmid20731020">{{cite journal |author=Nash KL, Woodall T, Brown AS, Davies SE, Alexander GJ |title=Hepatocellular carcinoma in patients with chronic hepatitis C virus infection without cirrhosis |journal=[[World Journal of Gastroenterology : WJG]] |volume=16 |issue=32 |pages=4061–5 |year=2010 |month=August |pmid=20731020 |pmc=2928460 |doi= |url=http://www.wjgnet.com/1007-9327/full/v16/i32/4061.htm |accessdate=2012-02-26}}</ref> | |||
==Prognosis== | ==Prognosis== |
Revision as of 02:50, 27 February 2012
Hepatitis C |
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Hepatitis C natural history On the Web |
American Roentgen Ray Society Images of Hepatitis C natural history |
Risk calculators and risk factors for Hepatitis C natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]; Assistant Editor-In-Chief: Nina Axiotakis [3]
Natural History
Of every 100 people infected with the Hepatitis C virus, about
- 75–85 people will develop chronic Hepatitis C virus infection; of those,
- 60–70 people will go on to develop chronic liver disease
- 5–20 people will go on to develop cirrhosis over a period of 20–30 years
- 1–5 people will die from cirrhosis or liver cancer
Complications
- Hepatitis C infection can continue over many years leading to chronic hepatitis
- Over years, liver may undergo extensive damage and scarring resulting in cirrhosis
- Liver failure
- Hepatocellular carcinoma may occur in patients with chronic hepatitis C infection.[1]
Prognosis
- Acute Infection
- 20% recover
- 80% have persistent infection
- 30% of these patients develop cirrhosis
- Genotype
- Predicts response to treatment
- Genotype 1 less responsive than types 2 & 3
References
- ↑ Nash KL, Woodall T, Brown AS, Davies SE, Alexander GJ (2010). "Hepatocellular carcinoma in patients with chronic hepatitis C virus infection without cirrhosis". World Journal of Gastroenterology : WJG. 16 (32): 4061–5. PMC 2928460. PMID 20731020. Retrieved 2012-02-26. Unknown parameter
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