Hepatitis C history and symptoms: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
 
(10 intermediate revisions by 5 users not shown)
Line 1: Line 1:
{{#widget:SchemaSnippet}}
{{#widget:SchemaSnippet}}
{{Hepatitis C}}
{{Hepatitis C}}
{{CMG}}
{{CMG}}; {{AE}} {{MehdiP}}, {{JA}}
==Overview==
==Overview==
Acute HCV infection is often asymptomatic and may only manifest as [[fatigue]] and low grade [[fever]]. Patients with chronic infection may present late with symptoms of liver [[cirrhosis]]. Patients are often diagnosed incidentally following an abnormal [[liver function test]] panel.
Acute HCV infection is often asymptomatic and may only manifest as [[fatigue]] and a low grade [[fever]]. Patients with chronic infection may present late with symptoms of liver [[cirrhosis]]. Patients are often diagnosed incidentally following an abnormal [[liver function test]] panel.


==History and Symptoms==
==History and Symptoms==
Approximately 70%–80% of people with acute Hepatitis C do not develop any symptoms early in the disease course. The majority of patients with chronic hepatitis C present at an advanced disease stage, usually due to the manifestations of liver cirrhosis. In asymptomatic patients, hepatitis C is often detected following the incidental finding of abnormal liver function tests.<ref name="pmid20521755">{{cite journal| author=Wilkins T, Malcolm JK, Raina D, Schade RR| title=Hepatitis C: diagnosis and treatment. | journal=Am Fam Physician | year= 2010 | volume= 81 | issue= 11 | pages= 1351-7 | pmid=20521755 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20521755  }} </ref> If symptoms occur, the average time is 6–7 weeks after exposure, but this can range from 2 weeks to 6 months. Patients may develop mild to severe symptoms soon after being infected, including:<ref name="pmid20521755">{{cite journal| author=Wilkins T, Malcolm JK, Raina D, Schade RR| title=Hepatitis C: diagnosis and treatment. | journal=Am Fam Physician | year= 2010 | volume= 81 | issue= 11 | pages= 1351-7 | pmid=20521755 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20521755  }} </ref>
Approximately 70%–80% of people with acute hepatitis C do not develop any [[symptoms]] early in the disease course. The majority of patients with chronic hepatitis C present at an advanced disease stage, usually due to the manifestations of the liver [[cirrhosis]]. Although asymptomatic, up to two-third [[patients]] present with extra-[[hepatic|liver]] manifestations.<ref name="CacoubLongo2021">{{cite journal|last1=Cacoub|first1=Patrice|last2=Longo|first2=Dan L.|last3=Saadoun|first3=David|title=Extrahepatic Manifestations of Chronic HCV Infection|journal=New England Journal of Medicine|volume=384|issue=11|year=2021|pages=1038–1052|issn=0028-4793|doi=10.1056/NEJMra2033539}}</ref>
In asymptomatic patients, hepatitis C is often detected following the incidental finding of abnormal [[liver function tests]].<ref name="pmid20521755">{{cite journal| author=Wilkins T, Malcolm JK, Raina D, Schade RR| title=Hepatitis C: diagnosis and treatment. | journal=Am Fam Physician | year= 2010 | volume= 81 | issue= 11 | pages= 1351-7 | pmid=20521755 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20521755  }} </ref> If symptoms occur, the average time is 6–7 weeks after exposure, but this can range from 2 weeks to 6 months. Patients may develop mild to severe symptoms soon after being infected, including:<ref name="pmid20521755">{{cite journal| author=Wilkins T, Malcolm JK, Raina D, Schade RR| title=Hepatitis C: diagnosis and treatment. | journal=Am Fam Physician | year= 2010 | volume= 81 | issue= 11 | pages= 1351-7 | pmid=20521755 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20521755  }} </ref>
 
=== Constitutional Sypmtoms ===
*[[Fever]]
*[[Fever]]
*[[Fatigue]]
*[[Fatigue]]
*[[Anorexia]]
*[[Anorexia]]
*[[Arthralgia]]
*[[Nausea]]
*[[Nausea]]
*[[Vomiting]]
*[[Vomiting]]
*[[Abdominal pain]]
 
*Dark-colored urine
=== [[Jaundice]] ===
*[[Acholic stools]]
Indicate advanced liver disease. Less commonly seen in acute infection.
*[[Arthralgia]]
 
*[[Icterus]]
=== [[Ascites]] ===
*[[Jaundice]]
Indicate advanced live disease.
 
=== Extrahepatic manifestations ===
* [[Vasculitis]],
* Renal injury and dark-colored urine
* Skin manifestations such as [[porphyria cutanea tarda]]


==References==
==References==
{{Reflist|1}}
{{Reflist|1}}


[[Category:Hepatitis|C]]
{{WH}}
{{WS}}
 
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:FinalQCRequired]]
[[Category:Emergency mdicine]]
[[Category:Disease]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Disease]]
[[Category:Hepatology]]
 
 
{{WH}}
{{WS}}

Latest revision as of 23:14, 12 June 2021

Hepatitis Main Page

Hepatitis C

Home

Patient Info

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology & Demographics

Risk Factors

Screening

Differentiating Hepatitis C from other Diseases

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms

Physical Examination

Lab Tests

Electrocardiogram

Chest X Ray

CT

MRI

Ultrasound

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

Hepatitis C history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hepatitis C history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hepatitis C history and symptoms

CDC on Hepatitis C history and symptoms

Hepatitis C history and symptoms in the news

Blogs on Hepatitis C history and symptoms

Directions to Hospitals Treating Hepatitis C

Risk calculators and risk factors for Hepatitis C history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2], Javaria Anwer M.D.[3]

Overview

Acute HCV infection is often asymptomatic and may only manifest as fatigue and a low grade fever. Patients with chronic infection may present late with symptoms of liver cirrhosis. Patients are often diagnosed incidentally following an abnormal liver function test panel.

History and Symptoms

Approximately 70%–80% of people with acute hepatitis C do not develop any symptoms early in the disease course. The majority of patients with chronic hepatitis C present at an advanced disease stage, usually due to the manifestations of the liver cirrhosis. Although asymptomatic, up to two-third patients present with extra-liver manifestations.[1] In asymptomatic patients, hepatitis C is often detected following the incidental finding of abnormal liver function tests.[2] If symptoms occur, the average time is 6–7 weeks after exposure, but this can range from 2 weeks to 6 months. Patients may develop mild to severe symptoms soon after being infected, including:[2]

Constitutional Sypmtoms

Jaundice

Indicate advanced liver disease. Less commonly seen in acute infection.

Ascites

Indicate advanced live disease.

Extrahepatic manifestations

References

  1. Cacoub, Patrice; Longo, Dan L.; Saadoun, David (2021). "Extrahepatic Manifestations of Chronic HCV Infection". New England Journal of Medicine. 384 (11): 1038–1052. doi:10.1056/NEJMra2033539. ISSN 0028-4793.
  2. 2.0 2.1 Wilkins T, Malcolm JK, Raina D, Schade RR (2010). "Hepatitis C: diagnosis and treatment". Am Fam Physician. 81 (11): 1351–7. PMID 20521755.

Template:WH Template:WS

Cookies help us deliver our services. By using our services, you agree to our use of cookies.

Navigation menu