Hepatitis B history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

History

Part of the initial evaluation for HBV infection include a thorough patient history focusing on potential modes and timing of infection.[1]

Aspects covered in the patient's history include:[1]

  • Exposure to blood and/or blood products
  • Injection drug use(IDU)
  • Sexual exposure
  • Occupational exposure
  • Family history of HBV
  • Recent history of invasive procedures performed in non-hospital health care settings, including hemodialysis centers and long-term care facilities[2]


History taking among immigrants from regions with a high prevalence of HBV should include questions regarding family history of acute and/or chronic liver disease, rituals in which shared and non-sterile instruments were used such as scarification and piercing, and traditional medical procedures.[1]


In patients with chronic HBV, history taking should focus on the following:[1]

  • Risk factors for coinfection
  • Medication history
  • Smoking status
  • Alcohol consumption
  • Drug abuse
  • Sexual activity
  • History of previous HBV treatment
  • Anti-retroviral drug regimen if coinfected with HIV

Symptoms

Approximately, 50% of adults with acute HBV infections are asymptomatic. However, clinical symptoms occur more often in adults than in infants or children, who usually have an asymptomatic acute course.[3]

Symptoms can include:



References

  1. 1.0 1.1 1.2 1.3 Klug WA, Capelhuchnick P, Gagliardi D, Oriente L (1979). "[Intestinal occlusion caused by spontaneous hematoma of the colon in a leukemia patient]". Rev Paul Med. 93 (1–2): 21–4. PMID 288148.
  2. Thompson ND, Perz JF, Moorman AC, Holmberg SD (2009). "Nonhospital health care-associated hepatitis B and C virus transmission: United States, 1998-2008". Ann Intern Med. 150 (1): 33–9. PMID 19124818.
  3. Center for Disease Control and Prevention. Hepatitis B Epidemiology and Prevention of Vaccine-Preventable Diseases 2012.http://www.cdc.gov/vaccines/pubs/pinkbook/hepb.html

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