Hemoptysis resident survival guide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Definition

Hemoptysis is the expectoration of blood from the respiratory system.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Hemoptysis may be a life-threatening condition depending on the severity of bleeding and must be treated as such irrespective of the causes.

Common Causes

  • Pulmonary disease
    • Tuberculosis
    • Aspergilloma
    • Lung malignancy
      • Bronchial carcinoma, adenoma
      • Metastatic lung cancer
    • Chronic obstructive airway disease
    • Lung abscess
    • Cystic fibrosis [1]
    • Sarcoidosis
    • Vasculitis [2]
      • Wegener's granulomatosis
      • Behcet's disease
  • Cardiovascular disease
    • Pulmonary artery arteriovenous malformation
    • Pulmonary embolism
    • pulmonary hypertension
    • Bronchial artery aneurysm
    • Thoracic aortic aneurysm
    • Aortobronchial fistula
  • Others
    • Coagulopathy
      • Von Willebrand disease
      • Haemophilia
      • Trombocytopenia
    • Iatrogenic
      • Anticoagulation
    • Trauma

Management

 
 
 
 
 
 
 
Characterise the symptoms [3]

❑ Coughing up blood
Chest pain
Tachypnea
Dyspnea
Fever
Obtein detalled history
❑ Recent travel H/O
❑ Recent drug H/O
❑ Family H/O

❑ Systemic illness H/O
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Asses volume stauts

❑ General condition
❑ Heart rate

Blood pressure

Respiratory rate

❑ Mucosa

Pulmonary reserve

Examine the patient

❑ Exclude hemorrhagic sites from nasopharynx and gastrointestinal track

❑ Skin (paleness)

Respiratory system (use accessory respiratory muscles, murmur)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Order lab

Complete blood count

Arterial blood gas

❑ Coagulation profile

Electrolytes

❑ Blood typing and cross match

❑ Liver and renal function test
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hemoptysis
 
 
Upper gastrointestinal bleeding
 
 
Nasopharynx bleed
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Follow Upper gastrointestinal bleeding resident survival guide
 
 
Refer to otolaryngologist
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Management of Mild to Moderate Hemoptysis

The algorithm is based on the American Family Physician Journal of hemoptysis: Diagnosis and Management 1. [4]

 
 
 
 
 
 
 
 
 
 
 
 
Hemoptysis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Mild hemoptysis
❑ <30 cc in 24 hours [5]
 
 
 
 
 
 
 
 
 
 
 
 
Moderate hemoptysis
❑ 30-200 cc in 24 hours [6]
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Chest X-ray (CXR)
 
 
 
 
 
 
 
 
 
 
 
 
Chest X-ray and CT
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Diagnose found
 
 
 
 
 
Diagnose unknown
 
 
 
 
Diagnose found
 
 
 
 
 
Diagnose unknown
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Treat underlying disease
 
 
 
 
 
Risk of malignancy[7]

Smoking

❑ Occupational exposure

❑ Family history

❑ Previous cancer treatment
 
 
 
 
Treat underlying disease
 
 
 
 
 
Bronchoscopy to find diagnosis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
yes
 
 
 
 
 
No
 
 
 
 
Diagnose found
 
 
 
 
 
Diagnose unknown
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
CT or bronchoscopy to find diagnosis
 
 
 
 
 
Close monitoring
 
 
 
 
Treat underlying disease
 
 
 
 
 
{{{ Go4 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Diagnose found
 
 
 
 
 
Diagnose unknown
 
If hemoptysis persist consult with pneumonologist
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Treat underlying Disease
 
 
 
 
 
Close monitoring
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Management of Massive Hemoptysis

The algorithm is based on the Society of Critical Care Medicine Journal of clinical assessment and management of massive hemoptysis. [8]

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ A01 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ B01 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ C01 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ C02 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ D01 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ D02 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ E01 }}}
 
 
 
 
 
 
 
 
 
 
 
{{{ E02 }}}
 
 
 
 
 
{{{ E03 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ F01 }}}
 
{{{ F02 }}}
 
 
 
 
 
 
 
 
 
 
 
{{{ F03 }}}
 
{{{ F04 }}}
 
{{{ F05 }}}
 
{{{ F06 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ G01 }}}
 
{{{ G02 }}}
 
 
 
 
 
 
 
 
 
 
 
{{{ G03 }}}
 
{{{ G04 }}}
 
{{{ G05 }}}
 
{{{ G06 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ H01 }}}
 
{{{ H02 }}}
 
 
 
 
 
 
 
 
 
{{{ H03 }}}
 
 
 
 
 
{{{ H04 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ I01 }}}
 
{{{ I02 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
{{{ J01 }}}
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Do's

  • Investigate profusely the patients medical history for possible etiology.
  • Intubate patient with massive hemoptysis to protect airway.
  • Determine volume and rate of blood.
  • All patients need to have oxygen to maintain oxyhemoglobin saturation.
  • If the bleeding is located in one lung, the patient with massive hemoptysis must be placed on lateral deceit toward side of bleeding.
  • Treat massive hemoptysis in a ICU.

Dont's

  • Chest CT shouldn't

References

  1. name="pmid20058006">Chun JY, Morgan R, Belli AM (2010). "Radiological management of hemoptysis: a comprehensive review of diagnostic imaging and bronchial arterial embolization". Cardiovasc Intervent Radiol. 33 (2): 240–50. doi:10.1007/s00270-009-9788-z. PMID 20058006.
  2. name="pmid10834728">Jean-Baptiste E (2000). "Clinical assessment and management of massive hemoptysis". Crit Care Med. 28 (5): 1642–7. PMID 10834728.
  3. Parrillo, Joseph E.; Dellinger, R. Phillip. (2014). Critical care medicine : principles of diagnosis and management in the adul. Philadelphia, PA: Elsevier/Saunders. ISBN 978-0-323-08929-6.
  4. name="pmid16225028">Bidwell JL, Pachner RW (2005). "Hemoptysis: diagnosis and management". Am Fam Physician. 72 (7): 1253–60. PMID 16225028.
  5. name="pmid12243312">Fidan A, Ozdoğan S, Oruç O, Salepçi B, Ocal Z, Cağlayan B (2002). "Hemoptysis: a retrospective analysis of 108 cases". Respir Med. 96 (9): 677–80. PMID 12243312.
  6. name="pmid12243312">Fidan A, Ozdoğan S, Oruç O, Salepçi B, Ocal Z, Cağlayan B (2002). "Hemoptysis: a retrospective analysis of 108 cases". Respir Med. 96 (9): 677–80. PMID 12243312.
  7. Parkin DM, Boyd L, Walker LC (2011). "16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010". Br J Cancer. 105 Suppl 2: S77–81. doi:10.1038/bjc.2011.489. PMC 3252065. PMID 22158327.
  8. name="pmid10834728">Jean-Baptiste E (2000). "Clinical assessment and management of massive hemoptysis". Crit Care Med. 28 (5): 1642–7. PMID 10834728.


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