Helicobacter pylori infection diagnostic test

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Nonendoscpic diagnostic studies

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  • Antibody testing is inexpensive and widely available but poor PPV in populations with a low prevalence of H. pylori infection limits its usefulness in clinical practice.

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  • The UBTs and fecal antigen tests provide reliable means of identifying active H. pylori infection before antibiotic therapy.

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  • The UBT is the most reliable nonendoscopic test to document eradication of H. pylori infection. |-

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  • The monclonal fecal antigen test provides another nonendoscopic means of establishing H. pylori cure after antibiotic treatment.

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  • Testing to prove H. pylori eradication appears to be most accurate if performed at least 4 wk after the completion of antibiotic therapy.

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References