Hantavirus infection medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There is no specific treatment, cure, or vaccine for hantavirus infection. However, we do know that if infected individuals are recognized early and receive medical care in an intensive care unit, they may do better.

Medical Therapy

In intensive care, patients are intubated and given oxygen therapy to help them through the period of severe respiratory distress.

The earlier the patient is brought in to intensive care, the better. If a patient is experiencing full distress, it is less likely the treatment will be effective.

Therefore, if you have been around rodents and have symptoms of fever, deep muscle aches, and severe shortness of breath, see your doctor immediately. Be sure to tell your doctor that you have been around rodents-this will alert your physician to look closely for any rodent-carried disease, such as HPS.

  • Hanta virus treatment[1]
  • Supportive therapy
  • ICU management should include careful assessment, monitoring and adjustment of volume status and cardiac function, including inotropic and vasopressor support if needed.
  • Fluids should be administered carefully due to the potential for capillary leakage.
  • Supplemental oxygen should be administered if patients become hypoxic.
  • Equipment and materials for intubation and mechanical ventilation should be readily available since onset of respiratory failure may be precipitous.
  • Note (1): There is no specific treatment or cure for hantavirus infection.
  • Note (2): Treatment of patients with HPS remains supportive in nature.
  • Note (3): Patients should receive appropriate, broad-spectrum antibiotic therapy while awaiting confirmation of a diagnosis of HPS. Care during the initial stages of the disease should include antipyretics and analgesia as needed.
  • Note (4): If there is a high degree of suspicion of Hantavirus pulmonary syndrome, patients should be immediately transferred to an emergency department or intensive care unit (ICU) for close monitoring and care.
  • Note (5): if the individual is experiencing fever and fatigue and has a history of potential rural rodent exposure, together with shortness of breath, would be strongly suggestive of Hantavirus pulmonary syndrome[2]

References

  1. Template:Citeweb
  2. Crowley MR, Katz RW, Kessler R, Simpson SQ, Levy H, Hallin GW; et al. (1998). "Successful treatment of adults with severe Hantavirus pulmonary syndrome with extracorporeal membrane oxygenation". Crit Care Med. 26 (2): 409–14. PMID 9468181.

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