Hamartoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
The prevalence of pulmonary hamartoma is approximately 0.25% in general population. The prevalence of other hamartomas remains unknown.[1][2] Hamartomatous tumors are usually first diagnosed among adult patients and are uncommon in children.[1] Overall, all hamartomas affect males more commonly than females.[1]
Epidemiology and demographics
Prevalence
- The prevalence of pulmonary hamartoma is approximately 0.25% in general population.[1]
- Pulmonary hamartomas are estimated to be 8% of all lung neoplasms. Most lesions are diagnosed incidentally.[3][4]
- The prevalence of other hamartomas remains unknown.
Age
- Pulmonary hamartomas are usually first diagnosed among patients in the 4th and 7th decades of life.[1]
- Pulmonary hamartomas are very uncommon in children.[1]
- Hypothalamic hamartomas are usually first diagnosed during puberty.[2]
- Cardiac hamartomas are usually first diagnosed among adolescents and young adults.[5]
- Kidney hamartomas are usually first diagnosed among middle age adults.[6]
- The median age of presentation for kidney hamartomas is 43 years.[6]
Gender
- Males are more commonly affected with pulmonary hamartomas than females. The male to female ratio is approximately ~2-3:1 ratio.[1]
- Males are more commonly affected with hypothalamic hamartomas than females. The male to female ratio is approximately 1.3:1 ratio.
Race
- Hypothalamic hamartoma usually affects individuals of all ethnic groups equally.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Hansen CP, Holtveg H, Francis D, Rasch L, Bertelsen S (1992). "Pulmonary hamartoma". J. Thorac. Cardiovasc. Surg. 104 (3): 674–8. PMID 1513155.
- ↑ 2.0 2.1 Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS (2003). "Hypothalamic hamartomas: seven cases and review of the literature". Epilepsy Behav. 4 (3): 246–58. PMID 12791326.
- ↑ Murray J, Kielkowski D, Leiman G (1991). "The prevalence and age distribution of peripheral pulmonary hamartomas in adult males. An autopsy-based study". S. Afr. Med. J. 79 (5): 247–9. PMID 2011801.
- ↑ Pulmonary hamartoma.Dr Henry Radiopedia.http://radiopaedia.org/articles/pulmonary-hamartoma-1 Accessed on December 08,2015
- ↑ Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, Ozawa T, Nakayama H, Shinozaki M, Sasai D, Ishiwatari T, Takuma K, Shibuya K (2012). "Literature survey on epidemiology and pathology of cardiac fibroma". Eur. J. Med. Res. 17: 5. doi:10.1186/2047-783X-17-5. PMC 3351722. PMID 22472419.
- ↑ 6.0 6.1 Eble JN (1998). "Angiomyolipoma of kidney". Seminars in Diagnostic Pathology. 15 (1): 21–40. PMID 9503504.