HLA-B associated transcript 3

Revision as of 18:02, 4 September 2012 by WikiBot (talk | contribs) (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search


HLA-B associated transcript 3
PDB rendering based on 1wx9.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols BAT3 ; D6S52E; G3
External IDs Template:OMIM5 Template:MGI HomoloGene: 3409
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

HLA-B associated transcript 3, also known as BAT3, is a human gene.[1]

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is a nuclear protein. It has been implicated in the control of apoptosis and regulating heat shock protein. There are three alternatively spliced transcript variants described for this gene.[1]

References

  1. ↑ 1.0 1.1 "Entrez Gene: BAT3 HLA-B associated transcript 3".

Further reading

  • Takayama S, Reed JC (2001). "Molecular chaperone targeting and regulation by BAG family proteins". Nat. Cell Biol. 3 (10): E237–41. doi:10.1038/ncb1001-e237. PMID 11584289.
  • Cross SJ, Tonks S, Trowsdale J, Campbell RD (1992). "Novel detection of restriction fragment length polymorphisms in the human major histocompatibility complex". Immunogenetics. 34 (6): 376–84. PMID 1684176.
  • Banerji J, Sands J, Strominger JL, Spies T (1990). "A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain". Proc. Natl. Acad. Sci. U.S.A. 87 (6): 2374–8. PMID 2156268.
  • Spies T, Bresnahan M, Strominger JL (1989). "Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B". Proc. Natl. Acad. Sci. U.S.A. 86 (22): 8955–8. PMID 2813433.
  • Spies T, Blanck G, Bresnahan M; et al. (1989). "A new cluster of genes within the human major histocompatibility complex". Science. 243 (4888): 214–7. PMID 2911734.
  • Ozaki T, Hanaoka E, Naka M; et al. (1999). "Cloning and characterization of rat BAT3 cDNA". DNA Cell Biol. 18 (6): 503–12. doi:10.1089/104454999315222. PMID 10390159.
  • Thress K, Song J, Morimoto RI, Kornbluth S (2001). "Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper". EMBO J. 20 (5): 1033–41. doi:10.1093/emboj/20.5.1033. PMID 11230127.
  • Manchen ST, Hubberstey AV (2001). "Human Scythe contains a functional nuclear localization sequence and remains in the nucleus during staurosporine-induced apoptosis". Biochem. Biophys. Res. Commun. 287 (5): 1075–82. doi:10.1006/bbrc.2001.5701. PMID 11587531.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
  • Xie T, Rowen L, Aguado B; et al. (2004). "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse". Genome Res. 13 (12): 2621–36. doi:10.1101/gr.1736803. PMID 14656967.
  • Lehner B, Semple JI, Brown SE; et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. PMID 14667819.
  • Wu YH, Shih SF, Lin JY (2004). "Ricin triggers apoptotic morphological changes through caspase-3 cleavage of BAT3". J. Biol. Chem. 279 (18): 19264–75. doi:10.1074/jbc.M307049200. PMID 14960581.
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.
  • Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
  • Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
  • Kumar R, Lutz W, Frank E, Im HJ (2004). "Immediate early gene X-1 interacts with proteins that modulate apoptosis". Biochem. Biophys. Res. Commun. 323 (4): 1293–8. doi:10.1016/j.bbrc.2004.09.006. PMID 15451437.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Stelzl U, Worm U, Lalowski M; et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.

Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=HLA-B_associated_transcript_3&oldid=716106"