Group B streptococcal infection natural history: Difference between revisions
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==Overview== | ==Overview== | ||
==Natural History== | |||
===GBS in Neonates=== | |||
Most newborns with early-onset disease have symptoms on the day of birth. Babies who develop late-onset disease may appear healthy at birth and develop symptoms of group B strep disease after the first week of life. | |||
===GBS in Pregnancy=== | |||
GBS colonization during pregnancy can be transient, intermittent, or persistent. Although some women with GBS colonization during a pregnancy will be colonized during subsequent pregnancies, a substantial proportion will not.<ref name="pmid18310374">{{cite journal| author=Cheng PJ, Chueh HY, Liu CM, Hsu JJ, Hsieh TT, Soong YK| title=Risk factors for recurrence of group B streptococcus colonization in a subsequent pregnancy. | journal=Obstet Gynecol | year= 2008 | volume= 111 | issue= 3 | pages= 704-9 | pmid=18310374 | doi=10.1097/AOG.0b013e318163cd6b | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18310374 }} </ref><ref name="pmid18669720">{{cite journal| author=Turrentine MA, Ramirez MM| title=Recurrence of group B streptococci colonization in subsequent pregnancy. | journal=Obstet Gynecol | year= 2008 | volume= 112 | issue= 2 Pt 1 | pages= 259-64 | pmid=18669720 | doi=10.1097/AOG.0b013e31817f5cb9 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18669720 }} </ref> In the absence of any intervention, an estimated 1%-2% of infants born to colonized mothers develop early-onset GBS infections.<ref name=CDC2007>CDC. Prevention of perinatal group B streptococcal disease: a public health perspective. MMWR 1996;45(No. RR-7).[http://www.cdc.gov/mmwr/preview/mmwrhtml/00043277.htm]</ref><ref name="pmid3931544">{{cite journal| author=Boyer KM, Gotoff SP| title=Strategies for chemoprophylaxis of GBS early-onset infections. | journal=Antibiot Chemother (1971) | year= 1985 | volume= 35 | issue= | pages= 267-80 | pmid=3931544 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3931544 }} </ref> | GBS colonization during pregnancy can be transient, intermittent, or persistent. Although some women with GBS colonization during a pregnancy will be colonized during subsequent pregnancies, a substantial proportion will not.<ref name="pmid18310374">{{cite journal| author=Cheng PJ, Chueh HY, Liu CM, Hsu JJ, Hsieh TT, Soong YK| title=Risk factors for recurrence of group B streptococcus colonization in a subsequent pregnancy. | journal=Obstet Gynecol | year= 2008 | volume= 111 | issue= 3 | pages= 704-9 | pmid=18310374 | doi=10.1097/AOG.0b013e318163cd6b | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18310374 }} </ref><ref name="pmid18669720">{{cite journal| author=Turrentine MA, Ramirez MM| title=Recurrence of group B streptococci colonization in subsequent pregnancy. | journal=Obstet Gynecol | year= 2008 | volume= 112 | issue= 2 Pt 1 | pages= 259-64 | pmid=18669720 | doi=10.1097/AOG.0b013e31817f5cb9 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18669720 }} </ref> In the absence of any intervention, an estimated 1%-2% of infants born to colonized mothers develop early-onset GBS infections.<ref name=CDC2007>CDC. Prevention of perinatal group B streptococcal disease: a public health perspective. MMWR 1996;45(No. RR-7).[http://www.cdc.gov/mmwr/preview/mmwrhtml/00043277.htm]</ref><ref name="pmid3931544">{{cite journal| author=Boyer KM, Gotoff SP| title=Strategies for chemoprophylaxis of GBS early-onset infections. | journal=Antibiot Chemother (1971) | year= 1985 | volume= 35 | issue= | pages= 267-80 | pmid=3931544 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3931544 }} </ref> | ||
Revision as of 13:04, 20 August 2014
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Group B Streptococcal Infection Microchapters |
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Differentiating Group B Streptococcal Infection from other Diseases |
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Group B streptococcal infection natural history On the Web |
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Directions to Hospitals Treating Group B streptococcal infection |
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Risk calculators and risk factors for Group B streptococcal infection natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [3]
Overview
Natural History
GBS in Neonates
Most newborns with early-onset disease have symptoms on the day of birth. Babies who develop late-onset disease may appear healthy at birth and develop symptoms of group B strep disease after the first week of life.
GBS in Pregnancy
GBS colonization during pregnancy can be transient, intermittent, or persistent. Although some women with GBS colonization during a pregnancy will be colonized during subsequent pregnancies, a substantial proportion will not.[1][2] In the absence of any intervention, an estimated 1%-2% of infants born to colonized mothers develop early-onset GBS infections.[3][4]
References
- ↑ Cheng PJ, Chueh HY, Liu CM, Hsu JJ, Hsieh TT, Soong YK (2008). "Risk factors for recurrence of group B streptococcus colonization in a subsequent pregnancy". Obstet Gynecol. 111 (3): 704–9. doi:10.1097/AOG.0b013e318163cd6b. PMID 18310374.
- ↑ Turrentine MA, Ramirez MM (2008). "Recurrence of group B streptococci colonization in subsequent pregnancy". Obstet Gynecol. 112 (2 Pt 1): 259–64. doi:10.1097/AOG.0b013e31817f5cb9. PMID 18669720.
- ↑ CDC. Prevention of perinatal group B streptococcal disease: a public health perspective. MMWR 1996;45(No. RR-7).[1]
- ↑ Boyer KM, Gotoff SP (1985). "Strategies for chemoprophylaxis of GBS early-onset infections". Antibiot Chemother (1971). 35: 267–80. PMID 3931544.