Glomus tumor epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

The exact incidence of glomus tumors is unknown. Solitary glomus tumors commonly affect young to middle aged individuals. Multiple glomus tumors commonly affect children. Females are more commonly affected with solitary glomus tumors (particularly subungual lesions) than males. Males are more commonly affected with multiple glomus tumors than females.

Epidemiology and Demographics

Incidence

  • The exact incidence of glomus tumors is unknown.
  • Glomus tumors account for 1-5% of all soft-tissue tumors of the upper extremity, occurring in most cases in the nail bed.[1]
  • The true incidence of glomus tumors could be even higher, likely as a result of misdiagnosis of many of these lesions as hemangiomas or venous malformations.
  • An epidemiologic relationship may exist between glomus tumors and neurofibromatosis, which most often produces subungual glomus tumors.[2]

Age

  • Solitary glomus tumors commonly affect young to middle aged individuals.
  • Multiple glomus tumors commonly affect children.
    • Multiple glomus tumors develop 11–15 years earlier than single lesions.
    • One third of the cases of multiple glomus tumors affect individuals younger than twenty years of age.

Gender

  • Females are more commonly affected with solitary glomus tumors (particularly subungual lesions) than males.
  • Multiple lesions are slightly more common in males.

References

  1. Nazerani S, Motamedi MH, Keramati MR (2010). "Diagnosis and management of glomus tumors of the hand". Tech Hand Up Extrem Surg. 14 (1): 8–13. doi:10.1097/BTH.0b013e3181c767d4. PMID 20216046.
  2. Harrison B, Moore AM, Calfee R, Sammer DM (2013). "The association between glomus tumors and neurofibromatosis". J Hand Surg Am. 38 (8): 1571–4. doi:10.1016/j.jhsa.2013.05.025. PMID 23849732.


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