Glomus tumor: Difference between revisions

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   OMIM          = 138000 |
   OMIM          = 138000 |
   MedlinePlus    = |
   MedlinePlus    = |
   eMedicineSubj  = derm |
   eMedicineSubj  = |
   eMedicineTopic = 167 |
   eMedicineTopic = |
   MeshID        = D005918 |
   MeshID        = D005918 |
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{{SI}}
{{Glomus tumor}}
{{CMG}}
{{CMG}}


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'''''Keywords and synonyms:''''' [[Paraganglioma]]
==[[Glomus tumor overview|Overview]]==


:'''''Glomus tumor''' was also the name used for a tumor now called a [[paraganglioma]].''
==[[Glomus tumor historical perspective|Historical Perspective]]==


==Overview==
==[[Glomus tumor pathophysiology|Pathophysiology]]==


A '''glomus tumor''' (glomangioma) is a rare [[benign]] [[neoplasm]], is a specialized arteriovenous anastomosis usually found in the skin of the extremities.  It arises from the [[glomus body]]
==[[Glomus tumor epidemiology and demographics|Epidemiology & Demographics]]==


==Presentation==
==[[Glomus tumor risk factors|Risk Factors]]==


They are usually solitary and small, and can be found under the fingernails.<ref name="pmid17875128">{{cite journal |author=Koç O, Kivrak AS, Paksoy Y |title=Subungual glomus tumour: magnetic resonance imaging findings |journal=Australasian radiology |volume=51 Spec No. |issue= |pages=B107–9 |year=2007 |pmid=17875128 |doi=10.1111/j.1440-1673.2007.01797.x |doi_brokendate=2008-06-22}}</ref> They can also be found on the [[tympanic membrane]].<ref name="pmid11981934">{{cite journal |author=De Candia A, Como G, Passon P, Pedace E, Bazzocchi M |title=Sonographic findings in glomus tympanicum tumor |journal=Journal of clinical ultrasound : JCU |volume=30 |issue=4 |pages=236–40 |year=2002 |pmid=11981934 |doi=10.1002/jcu.10058}}</ref>
==[[Glomus tumor screening|Screening]]==


They are often painful, and the pain is reproduced when the lesion is placed in cold water.
==[[Glomus tumor causes|Causes of Glomus tumor]]==


These tumors tend to have a bluish discoloration, although a white appearance is also noted. Elevation of the nail bed can occurr
==[[Glomus tumor differential diagnosis|Differentiating Glomus tumor from other Diseases]]==


==Frequency==
==[[Glomus tumor natural history|Natural History, Complications & Prognosis]]==
 
United States: The exact incidence of glomus tumors is unknown. The multiple variant is rare, accounting for less than 10% of all cases. The probable misdiagnosis of many of these lesions as hemangiomas or venous malformations also makes an accurate assessment of incidence difficult.
 
==Mortality/Morbidity==
 
The most common adverse effect is pain, which is usually associated with solitary lesions. Multiple tumors are less likely to be painful. In one report, a patient with more than 400 glomus tumors had thrombocytopenia as a result of platelet sequestration (ie, Kasabach-Merritt syndrome). Malignant glomus tumors, or glomangiosarcomas, are extremely rare and usually represent a locally infiltrative malignancy. However, metastases do occur and are usually fatal.
 
==Sex==
 
Solitary glomus tumors, particularly subungual lesions, are more common in females than in males. Multiple lesions are slightly more common in males.
 
==Age==
 
Solitary glomus tumors are more frequent in adults than in others. Multiple glomus tumors develop 10-15 years earlier than single lesions; about one third of the cases of multiple tumors occur in those younger than 20 years. Congenital glomus tumors are rare; they are plaquelike in appearance and are considered a variant of multiple glomus tumors.


==Diagnosis==
==Diagnosis==
[[Glomus tumor history and symptoms|History & Symptoms]] | [[Glomus tumor physical examination|Physical Examination]] | [[Glomus tumor laboratory tests|Lab Tests]] | [[Glomus tumor electrocardiogram|Electrocardiogram]] | [[Glomus tumor chest x ray|Chest X Ray]] | [[Glomus tumor CT|CT]] | [[Glomus tumor MRI|MRI]] | [[Glomus tumor echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Glomus tumor other imaging findings|Other Imaging Findings]] | [[Glomus tumor other diagnostic studies|Other Diagnostic Studies]]


===Physical Examination===
==Treatment==
 
[[Glomus tumor medical therapy|Medical Therapy]] | [[Glomus tumor surgery|Surgery]] | [[Glomus tumor primary prevention|Primary Prevention]] | [[Glomus tumor secondary prevention|Secondary Prevention]] | [[Glomus tumor cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Glomus tumor future or investigational therapies|Future or Investigational Therapies]]
====Ear Nose and Throat====
 
<div align="left">
<gallery heights="150" widths="150">
Image:Glomus Tympanicum Labeled.jpg|Picture of a left tympanic membrane with  a pulsating red mass occupying the inferior portion of the middle ear space.  The rest of the tympanic membrane is normal<ref>http://www.ghorayeb.com</ref>.
Image:Glomus Tympanicum Labeled Magnified.jpg|Glomus tympanicum magnified<ref>http://www.ghorayeb.com</ref>.
Image:Glomus Tympanicum DRUM 480x360 Labeled.jpg|This patient presented with a history of severe bleeding from the placement of a PE tube in her right ear.  On examination, the posterior half of the tympanic membrane was red and pulsating<ref>http://www.ghorayeb.com</ref>.
Image:Glomus Tympanicum 480x360 Labeled.jpg|Surgical picture of the above patient. A tympanomeatal flap has been elevated and reflected anteriorly to expose the glomus tympanicum that filled the posterior half of the middle ear space<ref>http://www.ghorayeb.com</ref>.
Image:Glomus Tympanicum CT Scan Axial Half.jpg|Axial CT scan showing the glomus tumor growing from the medial wall of the middle ear<ref>http://www.ghorayeb.com</ref>.
Image:Glomus Tympanicum CT Scan Coronal half.jpg|Coronal CT scan showing the glomus tympanicum tumor growing from the medial wall of the middle ear<ref>http://www.ghorayeb.com</ref>.
Image:Glomus Tympanicum SQ 344 Labeled.jpg|Surgical picture of glomus tympanicum in the eft middle ear.  The tympanomeatal flap has been raised and reflected anteriorly<ref>http://www.ghorayeb.com</ref>.
</gallery>
</div>
 
 
===MRI===
 
([http://www.radswiki.net Images courtesy of RadsWiki])
 
<gallery>
Image:Glomus-jugulare-001.jpg|Glomus tumor
Image:Glomus-jugulare-002.jpg|Glomus tumor
Image:Glomus-jugulare-003.jpg|Glomus tumor
Image:Glomus-jugulare-004.jpg|Glomus tumor
Image:Glomus-jugulare-005.jpg|Glomus tumor
Image:Glomus-jugulare-006.jpg|Glomus tumor
Image:Glomus-jugulare-007.jpg|Glomus tumor
Image:Glomus-jugulare-008.jpg|Glomus tumor
Image:Glomus-jugulare-009.jpg|Glomus tumor
Image:Glomus-jugulare-010.jpg|Glomus tumor
</gallery>


==See also==
==See also==
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==References==
==References==
* {{DukeOrtho|glomus_tumor}}
{{reflist|2}}


==External links==
* {{WhoNamedIt|synd|1584}}
* {{Chorus|00314}}
{{Epithelial neoplasms}}
{{Epithelial neoplasms}}
{{SIB}}
 
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Otolaryngology]]
[[Category:Otolaryngology]]
<br>
[[de:Glomustumor]]


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Revision as of 19:28, 18 January 2012

For patient information, click here

Glomus tumor
ICD-O: 8711/0
OMIM 138000
DiseasesDB 30732
MeSH D005918

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Keywords and synonyms: Paraganglioma

Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes of Glomus tumor

Differentiating Glomus tumor from other Diseases

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms | Physical Examination | Lab Tests | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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References

Template:Epithelial neoplasms


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