Gliomatosis cerebri natural history, complications, and prognosis

Jump to navigation Jump to search

Gliomatosis cerebri Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Gliomatosis cerebri from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice

Staging

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Gliomatosis cerebri natural history, complications, and prognosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Gliomatosis cerebri natural history, complications, and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Gliomatosis cerebri natural history, complications, and prognosis

CDC on Gliomatosis cerebri natural history, complications, and prognosis

Gliomatosis cerebri natural history, complications, and prognosis in the news

Blogs on Gliomatosis cerebri natural history, complications, and prognosis

Directions to Hospitals Treating Gliomatosis cerebri

Risk calculators and risk factors for Gliomatosis cerebri natural history, complications, and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Natural History

If left untreated, patients with meningioma may progress to develop focal neurological deficits, altered mental status, hydrocephalus, brain herniation, and ultimately death.

Complication

Common complications of gliomatosis cerebri include:[1]

Prognosis

Prognosis of gliomatosis cerebri is generally poor, and the 5-year survival rate of patients with treatment is approximately 17.7%.[2]

The median survival time of gliomatosis cerebri is 14 months.[3]

The prognosis of gliomatosis cerebri depends on the following:

  • Whether or not the tumor can be removed by surgery
  • Age of the patient
    • Age < 10 year is associated with worse prognosis
  • Gender of the patient
    • Males are associated with a better prognosis than females
  • Location of tumor
    • Infratentorial tumor is associated with shorter survival.[3]
  • Size of the tumor
  • Stage of the cancer
  • Whether the cancer has just been diagnosed or has recurred

Complications

References

  1. Treatment and prognosis of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri
  2. Inoue T, Kumabe T, Kanamori M, Sonoda Y, Watanabe M, Tominaga T (2010). "Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases". Neurosurg Rev. 34 (2): 197–208. doi:10.1007/s10143-010-0306-1. PMID 21301914.
  3. 3.0 3.1 Herrlinger U, Felsberg J, Küker W, Bornemann A, Plasswilm L, Knobbe CB; et al. (2002). "Gliomatosis cerebri: molecular pathology and clinical course". Ann Neurol. 52 (4): 390–9. doi:10.1002/ana.10297. PMID 12325066.


Template:WikiDoc Sources