Genital ulcer disease: Difference between revisions
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==Differentiating Genital Ulcer Diseases== | ==Differentiating Genital Ulcer Diseases== | ||
Sexually transmitted diseases characterized as GUD may present with similar manifestations and lesion characteristics. | |||
{| style="font-size: 90%;" | {| style="font-size: 90%;" | ||
! style="background: #4479BA; padding: 5px 5px;" rowspan=2 | {{fontcolor|#FFFFFF|Manifestation}} | ! style="background: #4479BA; padding: 5px 5px;" rowspan=2 | {{fontcolor|#FFFFFF|Manifestation}} | ||
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! style="background: #4479BA; padding: 5px 5px;" | {{fontcolor|#FFFFFF|Syphilis}} | ! style="background: #4479BA; padding: 5px 5px;" | {{fontcolor|#FFFFFF|Syphilis}} | ||
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| style="padding: 5px 5px; background: #DCDCDC;" | | | style="padding: 5px 5px; background: #DCDCDC;" | '''Cause''' | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | ''[[Haemophilus ducreyi]]'' | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | [[Herpes Simplex Virus]] (HSV-1 & HSV-2) | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | ''[[Klebsiella|Klebsiella granulomatis]]'' | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | ''[[Chlamydia trachomatis]]'' serovars L1, L2, or L3 | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | ''[[Treponema pallidum]]'' | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC;" | | | style="padding: 5px 5px; background: #DCDCDC;" | | ||
Revision as of 18:39, 2 February 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.
Synonyms and keywords: GUD
Overview
Genital ulcer disease (GUD) can be defined as diseases characterized by genital, anal, or perianal lesions that are ulcerative or pustular. GUD is typically caused by sexually transmitted infections (STI) but also by other non-STI conditions.
Sexually transmitted diseases characterized as GUD include:
Other conditions that are not sexually transmitted infections that may be associated with genital, anal, and perianal lesions include:[1]
Differentiating Genital Ulcer Diseases
Sexually transmitted diseases characterized as GUD may present with similar manifestations and lesion characteristics.
| Manifestation | Sexually Transmitted Disease | ||||
|---|---|---|---|---|---|
| Chancroid | Genital Herpes | Donovanosis | LGV | Syphilis | |
| Cause | Haemophilus ducreyi | Herpes Simplex Virus (HSV-1 & HSV-2) | Klebsiella granulomatis | Chlamydia trachomatis serovars L1, L2, or L3 | Treponema pallidum |
Laboratory Testing
A diagnosis based only on the patient’s medical history and physical examination frequently is inaccurate. Patients who have genital, anal, or perianal ulcers should be evaluated with, but not limited to, the following tests:
- Syphilis serology and darkfield examination
- Culture for HSV or PCR testing for HSV
- Serologic testing for type-specific HSV antibody
- Culture for Haemophilus ducreyi in areas of high chancroid prevalence
References
- ↑ 2015 Sexually Transmitted Diseases Treatment Guidelines. Centers for Disease Control and Prevention (June 4, 2015). http://www.cdc.gov/std/tg2015/genital-ulcers.htm Accessed February 2, 2016.