Generalized anxiety disorder risk factors: Difference between revisions
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*[[Negative affectivity]] ([[neuroticism]]) | *[[Negative affectivity]] ([[neuroticism]]) | ||
*[[Parental over-protection]]<ref name=DSMV>{{cite book | title = Diagnostic and statistical manual of mental disorders : DSM-5 | publisher = American Psychiatric Association | location = Washington, D.C | year = 2013 | isbn = 0890425558 }}</ref> | *[[Parental over-protection]]<ref name=DSMV>{{cite book | title = Diagnostic and statistical manual of mental disorders : DSM-5 | publisher = American Psychiatric Association | location = Washington, D.C | year = 2013 | isbn = 0890425558 }}</ref> | ||
===Genetics=== | |||
*Genes are attributed to about 33% of general anxiety disorder's variance.<ref name="pmid11578982">{{cite journal| author=Hettema JM, Neale MC, Kendler KS| title=A review and meta-analysis of the genetic epidemiology of anxiety disorders. | journal=Am J Psychiatry | year= 2001 | volume= 158 | issue= 10 | pages= 1568-78 | pmid=11578982 | doi=10.1176/appi.ajp.158.10.1568 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11578982 }} [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=12180459 Review in: Evid Based Ment Health. 2002 Aug;5(3):92] </ref> | |||
*Individuals with a genetic predisposition for GAD are more likely to develop GAD. | |||
**Especially in response to a life stressor.<ref name="pmid18639233">{{cite journal| author=Donner J, Pirkola S, Silander K, Kananen L, Terwilliger JD, Lönnqvist J et al.| title=An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders. | journal=Biol Psychiatry | year= 2008 | volume= 64 | issue= 8 | pages= 672-80 | pmid=18639233 | doi=10.1016/j.biopsych.2008.06.002 | pmc=2682432 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18639233 }} </ref> | |||
===Substance-Induced=== | |||
* | |||
* | |||
==References== | ==References== |
Revision as of 14:27, 8 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Irfan Dotani
Overview
Risk factors for developing generalized anxiety disorder include a positive family history, early adulthood, and a recent life stressor. Genetics along with substance-induced anxiety are large factors as well.
Risk Factors
- Behavioral inhibition
- Childhood adversities
- Genetic predisposition
- Harm avoidance
- Negative affectivity (neuroticism)
- Parental over-protection[1]
Genetics
- Genes are attributed to about 33% of general anxiety disorder's variance.[2]
- Individuals with a genetic predisposition for GAD are more likely to develop GAD.
- Especially in response to a life stressor.[3]
Substance-Induced
References
- ↑ Diagnostic and statistical manual of mental disorders : DSM-5. Washington, D.C: American Psychiatric Association. 2013. ISBN 0890425558.
- ↑ Hettema JM, Neale MC, Kendler KS (2001). "A review and meta-analysis of the genetic epidemiology of anxiety disorders". Am J Psychiatry. 158 (10): 1568–78. doi:10.1176/appi.ajp.158.10.1568. PMID 11578982. Review in: Evid Based Ment Health. 2002 Aug;5(3):92
- ↑ Donner J, Pirkola S, Silander K, Kananen L, Terwilliger JD, Lönnqvist J; et al. (2008). "An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders". Biol Psychiatry. 64 (8): 672–80. doi:10.1016/j.biopsych.2008.06.002. PMC 2682432. PMID 18639233.