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The most potent risk factor in the development of GISTs are age 50-80 and certain genetic syndromes like [[neurofibromatosis type 1]], [[carney-Stratakis syndrome]] and [[familial gastrointestinal stromal tumor syndrome]].
The most potent risk factor in the development of GISTs are age 50-80 and certain genetic syndromes like [[neurofibromatosis type 1]], [[carney-Stratakis syndrome]] and [[familial gastrointestinal stromal tumor syndrome]].
==Risk factors==
==Risk factors==
* Age-GISTs are more common in people aged 50 to 80
* Age-GISTs are more common in people aged 50 to 80.
*Genetic syndromes:
*Genetic syndromes:
:*Neurofibromatosis type 1 (or von Recklinghausen disease
:*Neurofibromatosis type 1 (or von Recklinghausen disease).
:*Carney-Stratakis syndrome- People with this rare, inherited condition have an increased risk of GISTs, as well as nerve tumors called paragangliomas.
:*Carney-Stratakis syndrome- People with this rare, inherited condition have an increased risk of GISTs, as well as nerve tumors called paragangliomas.
:*Familial gastrointestinal stromal tumor syndrome- It is a rare, inherited condition that leads to an increased risk of developing GISTs.
:*Familial gastrointestinal stromal tumor syndrome- It is a rare, inherited condition that leads to an increased risk of developing GISTs.


==References==
==References==

Revision as of 15:04, 3 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

The most potent risk factor in the development of GISTs are age 50-80 and certain genetic syndromes like neurofibromatosis type 1, carney-Stratakis syndrome and familial gastrointestinal stromal tumor syndrome.

Risk factors

  • Age-GISTs are more common in people aged 50 to 80.
  • Genetic syndromes:
  • Neurofibromatosis type 1 (or von Recklinghausen disease).
  • Carney-Stratakis syndrome- People with this rare, inherited condition have an increased risk of GISTs, as well as nerve tumors called paragangliomas.
  • Familial gastrointestinal stromal tumor syndrome- It is a rare, inherited condition that leads to an increased risk of developing GISTs.

References


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