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Revision as of 23:43, 30 August 2012
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Gastroesophageal reflux disease Microchapters |
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Differentiating Gastroesophageal Reflux Disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Gastroesophageal reflux disease causes On the Web |
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American Roentgen Ray Society Images of Gastroesophageal reflux disease causes |
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Directions to Hospitals Treating Gastroesophageal reflux disease |
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Risk calculators and risk factors for Gastroesophageal reflux disease causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
- Hereditary sensory and autonomic neuropathy type 1B
- Systemic sclerosis
- Autonomic neuropathy
- Esophageal achalasia
- Hiatus hernia
- Pharyngeal pouch
- Another paradoxical cause of GERD-like symptoms is not enough stomach acid (hypochlorhydria). The valve that empties the stomach into the intestines is triggered by acidity. If there is not enough acid, this valve does not open and the stomach contents are churned up into the esophagus. However, there is still enough acidity to irritate the esophagus.
- Hiatus hernia, which increases the likelihood of GERD due to mechanical and motility factors[1]
- Obesity: increasing body mass index is associated with more severe GERD[2]
- Zollinger-Ellison syndrome, which can be present with increased gastric acidity due to gastrin production
- Hypercalcemia, which can increase gastrin production, leading to increased acidity
- Scleroderma and systemic sclerosis, which can feature esophageal dysmotility
References
- ↑ Piesman M, Hwang I, Maydonovitch C, Wong RK (2007). "Nocturnal reflux episodes following the administration of a standardized meal. Does timing matter?". Am. J. Gastroenterol. 102 (10): 2128–2134. doi:10.1111/j.1572-0241.2007.01348.x. PMID 17573791.
- ↑ Ayazi S, Crookes P, Peyre C, (2007). "Objective documentation of the link between gastroesophageal reflux disease and obesity". Am. J. Gastroenterol. 102 (S): 138–139.