Gastric dumping syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

If left untreated dumping syndrome causes problems with digestion and absorption. This may in turn lead to symptoms such as nausea, vomiting, distention, abdominal pain and diarrhea.

Natural History, Complications, and Prognosis

Natural History

  • Over time, the symptoms of dumping syndrome tend to resolve.
  • The severe symptoms of dumping syndrome usually develop 3-24 months after surgery, and start with symptoms such as nausea, vomiting, distension, colicky abdominal pain, abdominal fullness and diarrhea.[1]
  • The symptoms of dumping syndrome usually continue in up to 1% to 2% of individuals within the first year after surgery.
  • If left untreated, patients with dumping syndrome may progress to develop early satiety, weight loss, malnutrition, hypoglycemia and nesidioblastosis.[2]

Complications

  • Possible complications of dumping syndrome include:
    • Conflict with food digestion, which results in reduced vitamin, mineral and nutrient absorption into the body.
    • Very low blood glucose that can cause mental confusion or incoherence after a meal.
    • Weight loss (out of fear of eating meals).

Prognosis

  • Prognosis is generally good, but dumping syndrome may interfere with the quality of life.

References

  1. Harries AD, Dew MJ, Crawley EO, Leach KG, Salaman JR, Rhodes J (1984). "Gastric emptying after surgery for the dumping syndrome". Postgrad Med J. 60 (705): 458–60. PMC 2417949. PMID 6462993.
  2. Mala T (2014). "Postprandial hyperinsulinemic hypoglycemia after gastric bypass surgical treatment". Surg Obes Relat Dis. 10 (6): 1220–5. doi:10.1016/j.soard.2014.01.010. PMID 25002326.

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