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{{Gallbladder cancer}}
{{Gallbladder cancer}}
 
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==Overview==
==Overview==
In 1777 Maxmillan de Stol described the [[gallbladder cancer]] and since studies have established in the identification of the [[disease]] and ineffective treatment of this disease.[[Gallbladder cancer]](GBC) are often clinically [[asymptomatic]] and an surprising finding at [[incision]], most commonly detected incidentally on [[Histology|histological]] examination.GBC is characterised by local [[invasion]], intensive regional [[lymphoid tissue]] [[metastasis]] and distant [[metastases]]. In general, GBC is that the most aggressive of the [[biliary]] cancers with the shortest median survival period.


== Historical Perspective ==
== Historical Perspective ==
* In between 1922 –1956, 4,271 [[cholecystectomy]] samples were collected and [[Adenocarcinoma|adenocarcinomas]] were noted.<ref name="pmid15957463">{{cite journal |vauthors=Puia IC, Vlad L, Iancu C, Al-Hajjar N, Pop F, Bălă O, Munteanu D |title=[Laparoscopic cholecystectomy for porcelain gallbladder] |language=Romanian |journal=Chirurgia (Bucur) |volume=100 |issue=2 |pages=187–9 |year=2005 |pmid=15957463 |doi= |url=}}</ref>
* In between 1962–1999, Stephen et al was to discover the association between [[calcium]] deposits and the development of [[gallbladder cancer]] is 7%.


== Discovery ==
== Discovery ==
* The association between [[calcium]] deposits in the gall bladder and the gallbladder cancer was made during 1797.<ref name="pmid11391368">{{cite journal |vauthors=Stephen AE, Berger DL |title=Carcinoma in the porcelain gallbladder: a relationship revisited |journal=Surgery |volume=129 |issue=6 |pages=699–703 |year=2001 |pmid=11391368 |doi=10.1067/msy.2001.113888 |url=}}</ref><ref name="pmid25568797">{{cite journal |vauthors=Gómez-López JR, De Andrés-Asenjo B, Ortega-Loubon C |title=A porcelain gallbladder and a rapid tumor dissemination |journal=Ann Med Surg (Lond) |volume=3 |issue=4 |pages=119–22 |year=2014 |pmid=25568797 |pmc=4284441 |doi=10.1016/j.amsu.2014.09.002 |url=}}</ref>
* The association between [[calcium]] deposits in the [[Gallbladder|gall bladder]] and the [[gallbladder cancer]] was made during 1797.<ref name="pmid11391368">{{cite journal |vauthors=Stephen AE, Berger DL |title=Carcinoma in the porcelain gallbladder: a relationship revisited |journal=Surgery |volume=129 |issue=6 |pages=699–703 |year=2001 |pmid=11391368 |doi=10.1067/msy.2001.113888 |url=}}</ref><ref name="pmid25568797">{{cite journal |vauthors=Gómez-López JR, De Andrés-Asenjo B, Ortega-Loubon C |title=A porcelain gallbladder and a rapid tumor dissemination |journal=Ann Med Surg (Lond) |volume=3 |issue=4 |pages=119–22 |year=2014 |pmid=25568797 |pmc=4284441 |doi=10.1016/j.amsu.2014.09.002 |url=}}</ref><ref name="pmid23423431">{{cite journal |vauthors=Schnelldorfer T |title=Porcelain gallbladder: a benign process or concern for malignancy? |journal=J. Gastrointest. Surg. |volume=17 |issue=6 |pages=1161–8 |year=2013 |pmid=23423431 |doi=10.1007/s11605-013-2170-0 |url=}}</ref>
* In between 1922 –1956, 4,271 [[cholecystectomy]] samples were collected and [[Adenocarcinoma|adenocarcinomas]] were noted.<ref name="pmid15957463">{{cite journal |vauthors=Puia IC, Vlad L, Iancu C, Al-Hajjar N, Pop F, Bălă O, Munteanu D |title=[Laparoscopic cholecystectomy for porcelain gallbladder] |language=Romanian |journal=Chirurgia (Bucur) |volume=100 |issue=2 |pages=187–9 |year=2005 |pmid=15957463 |doi= |url=}}</ref>
* Current literature evaluation shows that the general occurrence of [[Porcelain]] [[gallbladder cancer]], and [[gallbladder cancer]] most cancers is 0.2% and 0.8%, respectively—with a 15% concomitant occurrence.
* In between 1962–1999, Stephen et al was to discover the association between calcium deposits and the development of gallbladder cancer is 7%.
* Current literature evaluation shows that the general occurrence of Porciline gallbladder cancer, and gallbladder cancer most cancers is 0.2% and 0.8%, respectively—with a 15% concomitant occurrence.
* Other document notes the incidence of gallbladder malignancy in patients with gallbladder wall calcification to be 6%.<ref name="pmid23423431">{{cite journal |vauthors=Schnelldorfer T |title=Porcelain gallbladder: a benign process or concern for malignancy? |journal=J. Gastrointest. Surg. |volume=17 |issue=6 |pages=1161–8 |year=2013 |pmid=23423431 |doi=10.1007/s11605-013-2170-0 |url=}}</ref>
 
== Landmark Events in the Development of Treatment Strategies ==
* In 1887, [[cholecystectomy]] was first reported to treat gallbladder cancer.


==References==
==References==

Latest revision as of 02:01, 3 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

In 1777 Maxmillan de Stol described the gallbladder cancer and since studies have established in the identification of the disease and ineffective treatment of this disease.Gallbladder cancer(GBC) are often clinically asymptomatic and an surprising finding at incision, most commonly detected incidentally on histological examination.GBC is characterised by local invasion, intensive regional lymphoid tissue metastasis and distant metastases. In general, GBC is that the most aggressive of the biliary cancers with the shortest median survival period.

Historical Perspective

Discovery

References

  1. Puia IC, Vlad L, Iancu C, Al-Hajjar N, Pop F, Bălă O, Munteanu D (2005). "[Laparoscopic cholecystectomy for porcelain gallbladder]". Chirurgia (Bucur) (in Romanian). 100 (2): 187–9. PMID 15957463.
  2. Stephen AE, Berger DL (2001). "Carcinoma in the porcelain gallbladder: a relationship revisited". Surgery. 129 (6): 699–703. doi:10.1067/msy.2001.113888. PMID 11391368.
  3. Gómez-López JR, De Andrés-Asenjo B, Ortega-Loubon C (2014). "A porcelain gallbladder and a rapid tumor dissemination". Ann Med Surg (Lond). 3 (4): 119–22. doi:10.1016/j.amsu.2014.09.002. PMC 4284441. PMID 25568797.
  4. Schnelldorfer T (2013). "Porcelain gallbladder: a benign process or concern for malignancy?". J. Gastrointest. Surg. 17 (6): 1161–8. doi:10.1007/s11605-013-2170-0. PMID 23423431.


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