GRACE

WikiDoc Resources for GRACE
Articles
Most recent articles on GRACE Most cited articles on GRACE Review articles on GRACE Articles on GRACE in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on GRACE Images of GRACE Photos of GRACE Podcasts & MP3s on GRACE Videos on GRACE
Evidence Based Medicine
Cochrane Collaboration on GRACE Bandolier on GRACE TRIP on GRACE
Clinical Trials
Ongoing Trials on GRACE at Clinical Trials.gov Trial results on GRACE Clinical Trials on GRACE at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on GRACE NICE Guidance on GRACE NHS PRODIGY Guidance FDA on GRACE CDC on GRACE
Books
Books on GRACE
News
GRACE in the news Be alerted to news on GRACE News trends on GRACE
Commentary
Blogs on GRACE
Definitions
Definitions of GRACE
Patient Resources / Community
Patient resources on GRACE Discussion groups on GRACE Patient Handouts on GRACE Directions to Hospitals Treating GRACE Risk calculators and risk factors for GRACE
Healthcare Provider Resources
Symptoms of GRACE Causes & Risk Factors for GRACE Diagnostic studies for GRACE Treatment of GRACE
Continuing Medical Education (CME)
CME Programs on GRACE
International
GRACE en Espanol GRACE en Francais
Business
GRACE in the Marketplace Patents on GRACE
Experimental / Informatics
List of terms related to GRACE

Cardiology Network
Discuss GRACE further in the WikiDoc Cardiology Network
Adult Congenital
Biomarkers
Cardiac Rehabilitation
Congestive Heart Failure
CT Angiography
Echocardiography
Electrophysiology
Cardiology General
Genetics
Health Economics
Hypertension
Interventional Cardiology
MRI
Nuclear Cardiology
Peripheral Arterial Disease
Prevention
Public Policy
Pulmonary Embolism
Stable Angina
Valvular Heart Disease
Vascular Medicine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

GRACE (the Global Registry of Acute Coronary Events) is a large, prospective, multinational observational study of patients hospitalized with ACS. The aim of GRACE is to improve the quality of care for patients with ACS by describing differences in, and relationships between, patient characteristics, treatment practices, and in-hospital and postdischarge outcomes at hospitals around the world.

Methods

A total of 73 hospitals with on-site angiographic facility in 14 countries in North America, South America, Europe, Australia, and New Zealand were collaborated in GRACE and enrolled 24,189 patients.

Clusters were chosen on the basis of local demographic characteristics and hospital facilities to ensure a representative sample of patients with ACS from each country. Patients are identified by use of either active or passive surveillance approaches.

A standardized core case report form is completed for all patients. Information on patient demographics, medical history, acute symptoms, clinical characteristics, electrocardiographic findings, treatment approaches, and in-hospital outcomes is collected.

Patients are followed up at 6 months after hospital discharge to identify recurrent coronary events, use of various medications, and mortality.

Conclusions

The information collected from the GRACE project provides important and extensive insights into patient demographic and clinical characteristics, current practice patterns, and outcomes for patients with ACS from a number of countries throughout the world. Given the pressures of practicing evidence-based medicine, the results of GRACE should provide a multinational perspective into these important outcomes and identify practice variations that will allow new opportunities to improve patient care.