GOLM1

Golgi phosphoprotein 2
Identifiers
Symbols	GOLPH2 ; GP73; PSEC0257
External IDs	Template:OMIM5 Template:MGI HomoloGene: 12346
Gene ontology Cellular component Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Golgi phosphoprotein 2, also known as GOLPH2, is a human gene.

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes protein synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this encoded protein has been observed to be upregulated in response to viral infection. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Further reading

• Kladney RD, Bulla GA, Guo L; et al. (2000). "GP73, a novel Golgi-localized protein upregulated by viral infection". Gene. 249 (1–2): 53–65. PMID 10831838.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kladney RD, Cui X, Bulla GA; et al. (2002). "Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease". Hepatology. 35 (6): 1431–40. doi:10.1053/jhep.2002.32525. PMID 12029628.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bauer K, Zemlin M, Hummel M; et al. (2002). "Diversification of Ig heavy chain genes in human preterm neonates prematurely exposed to environmental antigens". J. Immunol. 169 (3): 1349–56. PMID 12133958.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Puri S, Bachert C, Fimmel CJ, Linstedt AD (2003). "Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption". Traffic. 3 (9): 641–53. PMID 12191016.CS1 maint: Multiple names: authors list (link)
• Kladney RD, Tollefson AE, Wold WS, Fimmel CJ (2002). "Upregulation of the Golgi protein GP73 by adenovirus infection requires the E1A CtBP interaction domain". Virology. 301 (2): 236–46. PMID 12359426.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519.CS1 maint: Multiple names: authors list (link)
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stelzl U, Worm U, Lalowski M; et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ramachandran P, Boontheung P, Xie Y; et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bachert C, Fimmel C, Linstedt AD (2007). "Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma". Traffic. 8 (10): 1415–23. doi:10.1111/j.1600-0854.2007.00621.x. PMID 17662025.CS1 maint: Multiple names: authors list (link)