Fibromuscular dysplasia history and symptoms: Difference between revisions

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{{Fibromuscular dysplasia}}
{{Fibromuscular dysplasia}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}}{{M.B}}  
==Overview==
==Overview==
Since Fibromuscular dysplasia can involve virtually every [[artery]] of the body, thus the clinical presentations of FMD vary widely and are determined by the [[vessel]]s territories that are involved. in the FMD,  multivessel involvement is common, then numerous and various manifestations may present.
Since Fibromuscular dysplasia can involve virtually every [[artery]] of the body, thus the clinical presentations of FMD vary widely and are determined by the [[vessel]]s territories that are involved.The clinical presentations of FMD may result from the [[stenosis]], occlusion, [[ischemia]], [[dissection]], [[rupture]] of [[aneurysm]]s and [[embolization]] of intravascular [[thrombi]] from dissection or aneurysms.<ref>{{Cite journal
The clinical presentations of FMD may result from the [[stenosis]], [[ischemia]], [[dissection]] and [[occlusion]],[[rupture]] of [[aneurysm]]s and [[embolization]] of intravascular [[thrombi]] from dissection or aneurysms.<ref>{{Cite journal
  | author = [[Jeffrey W. Olin]] & [[Brett A. Sealove]]
  | author = [[Jeffrey W. Olin]] & [[Brett A. Sealove]]
  | title = Diagnosis, management, and future developments of fibromuscular dysplasia
  | title = Diagnosis, management, and future developments of fibromuscular dysplasia
Line 31: Line 30:
==History and Symptoms==
==History and Symptoms==
*The majority of patients with fibromuscular dysplasia are asymptomatic.
*The majority of patients with fibromuscular dysplasia are asymptomatic.
*The hallmark of FMD is hypertension in women with the prime of their life, whereas  FMD can occur in both genders at any age its presentations across the lifespan.
*The hallmark of FMD is hypertension in women with the prime of their life, whereas  FMD can occur in both genders at any age, its presentations across the lifespan.
In general, the clinical presentations of FMD in women as compared with men are somewhat different. manifestations of [[cerebrovascular]] FMD  are more likely to occur in women, whereas manifestations of renal FMD, [[arterial dissection]]s and [[aneurysm]]s are more common in men.<ref>{{Cite journal
 
* In general, the clinical presentations of FMD in women as compared with men are somewhat different. Manifestations of [[cerebrovascular]] FMD  are more likely to occur in women, whereas manifestations of renal FMD, [[arterial dissection]]s and [[aneurysm]]s are more common in men.<ref>{{Cite journal
  | author = [[Esther S. H. Kim]], [[Jeffrey W. Olin]], [[James B. Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Barry T. Katzen]], [[Eva Kline-Rogers]], [[Pamela D. Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Christopher J. White]] & [[Heather L. Gornik]]
  | author = [[Esther S. H. Kim]], [[Jeffrey W. Olin]], [[James B. Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Barry T. Katzen]], [[Eva Kline-Rogers]], [[Pamela D. Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Christopher J. White]] & [[Heather L. Gornik]]
  | title = Clinical manifestations of fibromuscular dysplasia vary by patient sex: a report of the United States registry for fibromuscular dysplasia
  | title = Clinical manifestations of fibromuscular dysplasia vary by patient sex: a report of the United States registry for fibromuscular dysplasia
Line 43: Line 43:
  | doi = 10.1016/j.jacc.2013.07.038
  | doi = 10.1016/j.jacc.2013.07.038
  | pmid = 23954333
  | pmid = 23954333
}}</ref>
}}</ref>  
The most common presenting symptoms in 615 individuals from the United
States FMD Registry are as follows:
*Headache
*Pulsatile tinnitus
*Neck pain
*Flank or abdominal pain
The most common presenting signs of FMD are as follows:


. A positive history of [[headache]], pulsatile [[tinnitus]], [[neck pain]], and flank or abdominal pain are suggestive of FMD. The most common signs of FMD include [[hyperetension]] , [[cervical bruit]], [[abdominal bruit]], and [[transient ischemic attack]].
=== History ===
Patients with fibromuscular dysplasia may have a positive history of:
* [[headache]]  
* Pulsatile [[tinnitus]]  
* [[neck pain]]
* Flank or abdominal pain.


=== Common Symptoms <ref>{{Cite journal
| author = [[Jeffrey W. Olin]], [[James Froehlich]], [[Xiaokui Gu]], [[J. Michael Bacharach]], [[Kim Eagle]], [[Bruce H. Gray]], [[Michael R. Jaff]], [[Esther S. H. Kim]], [[Pam Mace]], [[Alan H. Matsumoto]], [[Robert D. McBane]], [[Eva Kline-Rogers]], [[Christopher J. White]] & [[Heather L. Gornik]]
| title = The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients
| journal = [[Circulation]]
| volume = 125
| issue = 25
| pages = 3182–3190
| year = 2012
| month = June
| doi = 10.1161/CIRCULATIONAHA.112.091223
| pmid = 22615343
}}</ref> ===
*[[Headache]]
*Pulsatile [[tinnitus]]
*[[Neck]] pain
*[[Flanks|Flank]] or [[abdominal]] pain


===Common Symptoms===
* The most common signs of FMD include [[hypertension]], cervical [[bruit]], [[abdominal bruit]], and [[transient ischemic attack]].
Common symptoms of [disease] include:
*[Symptom 1]
*[Symptom 2]
*[Symptom 3]


===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of [disease name] include
Less common symptoms of FMD include:
*[Symptom 1]
*[[Chest pain]] or [[shortness of breath]]
*[Symptom 2]
*[[Postprandial]] [[abdominal pain]]
*[Symptom 3]
*[[Claudication]]
*[[Amaurosis fugax]]
*[[Weight loss]]
*[[Horner syndrome]]
*[[Azotemia]]
*[[Myocardial infarction]]
*[[Mesenteric ischemia]]


==References==
==References==

Latest revision as of 20:00, 13 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.

Overview

Since Fibromuscular dysplasia can involve virtually every artery of the body, thus the clinical presentations of FMD vary widely and are determined by the vessels territories that are involved.The clinical presentations of FMD may result from the stenosis, occlusion, ischemia, dissection, rupture of aneurysms and embolization of intravascular thrombi from dissection or aneurysms.[1][2]

History and Symptoms

  • The majority of patients with fibromuscular dysplasia are asymptomatic.
  • The hallmark of FMD is hypertension in women with the prime of their life, whereas FMD can occur in both genders at any age, its presentations across the lifespan.
  • In general, the clinical presentations of FMD in women as compared with men are somewhat different. Manifestations of cerebrovascular FMD are more likely to occur in women, whereas manifestations of renal FMD, arterial dissections and aneurysms are more common in men.[3]

History

Patients with fibromuscular dysplasia may have a positive history of:

Common Symptoms [4]

Less Common Symptoms

Less common symptoms of FMD include:

References

  1. Jeffrey W. Olin & Brett A. Sealove (2011). "Diagnosis, management, and future developments of fibromuscular dysplasia". Journal of vascular surgery. 53 (3): 826–836. doi:10.1016/j.jvs.2010.10.066. PMID 021236620. Unknown parameter |month= ignored (help)
  2. Jeffrey W. Olin, Heather L. Gornik, J. Michael Bacharach, Jose Biller, Lawrence J. Fine, Bruce H. Gray, William A. Gray, Rishi Gupta, Naomi M. Hamburg, Barry T. Katzen, Robert A. Lookstein, Alan B. Lumsden, Jane W. Newburger, Tatjana Rundek, C. John Sperati & James C. Stanley (2014). "Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association". Circulation. 129 (9): 1048–1078. doi:10.1161/01.cir.0000442577.96802.8c. PMID 24548843. Unknown parameter |month= ignored (help)
  3. Esther S. H. Kim, Jeffrey W. Olin, James B. Froehlich, Xiaokui Gu, J. Michael Bacharach, Bruce H. Gray, Michael R. Jaff, Barry T. Katzen, Eva Kline-Rogers, Pamela D. Mace, Alan H. Matsumoto, Robert D. McBane, Christopher J. White & Heather L. Gornik (2013). "Clinical manifestations of fibromuscular dysplasia vary by patient sex: a report of the United States registry for fibromuscular dysplasia". Journal of the American College of Cardiology. 62 (21): 2026–2028. doi:10.1016/j.jacc.2013.07.038. PMID 23954333. Unknown parameter |month= ignored (help)
  4. Jeffrey W. Olin, James Froehlich, Xiaokui Gu, J. Michael Bacharach, Kim Eagle, Bruce H. Gray, Michael R. Jaff, Esther S. H. Kim, Pam Mace, Alan H. Matsumoto, Robert D. McBane, Eva Kline-Rogers, Christopher J. White & Heather L. Gornik (2012). "The United States Registry for Fibromuscular Dysplasia: results in the first 447 patients". Circulation. 125 (25): 3182–3190. doi:10.1161/CIRCULATIONAHA.112.091223. PMID 22615343. Unknown parameter |month= ignored (help)

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