Familial mediterranean fever overview: Difference between revisions

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==Overview==
==Overview==
Familial mediterranean fever is a [[genetic disorder|hereditary]] [[inflammation|inflammatory]] disorder that affects groups of patients originating from around the Mediterranean Sea (hence its name). It is prominently present in the Armenian people (up to 1 in 7 affected), Sephardi Jews (and, to a much lesser extent, Ashkenazi Jews), people from Turkey, the Arab countries and Lebanon.<ref name=Livneh>Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref>
Familial mediterranean fever is a [[genetic disorder|hereditary]] [[inflammation|inflammatory]] disorder that affects groups of patients originating from around the Mediterranean Sea (hence its name). It is prominently present in the Armenian people (up to 1 in 7 affected), Sephardi Jews (and, to a much lesser extent, Ashkenazi Jews), people from Turkey, the Arab countries and Lebanon.<ref name=Livneh>Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref>
==Historical Perspective==
A New York allergist, Dr Sheppard Siegal, first described the attacks of [[peritonitis]] in 1945; he termed this "benign paroxysmal peritonitis", as the disease course was essentially benign.<ref>Siegal S. Benign paroxysmal peritonitis. ''Ann Intern Med'' 1945;23:1-21.</ref> Dr Hobart Reimann, working in the American University in Beirut, described a more complete picture which he termed "periodic disease".<ref>Reiman HA. Periodic disease. Probable syndrome including periodic fever, benign paroxysmal peritonitis, cyclic neutropenia and intermittent arthralgia. ''[[Journal of the American Medical Association|JAMA]]'' 1948;136:239-44.</ref>


==References==
==References==

Revision as of 21:15, 5 March 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Familial mediterranean fever is a hereditary inflammatory disorder that affects groups of patients originating from around the Mediterranean Sea (hence its name). It is prominently present in the Armenian people (up to 1 in 7 affected), Sephardi Jews (and, to a much lesser extent, Ashkenazi Jews), people from Turkey, the Arab countries and Lebanon.[1]

Historical Perspective

A New York allergist, Dr Sheppard Siegal, first described the attacks of peritonitis in 1945; he termed this "benign paroxysmal peritonitis", as the disease course was essentially benign.[2] Dr Hobart Reimann, working in the American University in Beirut, described a more complete picture which he termed "periodic disease".[3]

References

  1. Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. Baillieres Best Pract Res Clin Rheumatol 2000;14(3):477-98. PMID 10985982.
  2. Siegal S. Benign paroxysmal peritonitis. Ann Intern Med 1945;23:1-21.
  3. Reiman HA. Periodic disease. Probable syndrome including periodic fever, benign paroxysmal peritonitis, cyclic neutropenia and intermittent arthralgia. JAMA 1948;136:239-44.

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